Protein Alignment Myd88 and myd88

DIOPT Version :9

• Sequence 1: NP_001260821.1
• Gene: Myd88 / 35956
• FlyBaseID: FBgn0033402
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_997979.2
• Gene: myd88 / 403145
• ZFINID: ZDB-GENE-040219-3
• Length: 284
• Species: Danio rerio
• Alignment Length: 302
• Identity: 76/302 - (25%)
• Similarity: 137/302 - (45%)
• Gaps: 41/302 - (13%)

  Fly    82 PLSALGIETRTQLSRMLNRKKVLRSEEGYQRDWRGISEL-----AKQKGFVDENANNPMDLVLIS 141
            |::||....|.:|...||....:.:      |||.::||     .:.|.|  |..:.|.:.||..
Zfish    13 PVTALNCSFRKKLGLFLNPTNTVAA------DWRTVAELMDFTYLEIKNF--EKRDCPFEKVLTD 69

  Fly   142 WSQRSPQTAKVGHLEHFLGIIDRWDVCDDIQENLAKDTQRFIMKQEQR--QTALVEACPPPPSDC 204
            |..|...|  |.:|...|...:|.||..:::|.|..|.::::.:|:::  |..:|::|.|...:
Zfish    70 WETRPDAT--VANLLSILEKAERKDVISELKEILDDDCRKYMERQQRKPLQVPVVDSCGPRTQE- 131

  Fly   205 FETNNNYSSSNNITVGQSVQILSDEDQRCVQMGQPLPRYNACVLYAEADIDHATEIMNNLESERY 269
                     ...:|:....|.|:.|            .::|.:.|.::||....|::..||...|
Zfish   132 ---------REGVTLYDDPQGLTPE------------TFDAFICYCQSDIQFVHEMIKQLEHTEY 175

  Fly   270 NLRLFLRHRDMLMGVPFEHVQLSHFMATRCNHLIVVLTEEFLRSPENTYLVNFTQKIQIENHTRK 334
            ||:|.:..||:|.|.....: .|..:..||..::||:::::|.|....:...|...:.....|::
Zfish   176 NLKLCVFDRDVLPGTCVWTI-ASELIEKRCKRMVVVISDDYLDSDACDFQTKFALSLCPGARTKR 239

  Fly   335 IIPILYKT-DMHIPQTLGIYTHIKYAGDSKLFNFWDKLARSL 375
            :||::||: ....|..|...|...|:.......||.:||::|
Zfish   240 LIPVVYKSMKRPFPSILRFLTICDYSKPCTQVWFWTRLAKAL 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myd88	NP_001260821.1	DD	90..172	CDD:301326	24/86 (28%)
		TIR_2	242..375	CDD:304906	36/133 (27%)
myd88	NP_997979.2	TIR	148..284	CDD:214587	37/135 (27%)
		Death_MyD88	21..98	CDD:260026	24/86 (28%)
		Intermediate domain. /evidence=ECO:0000250	102..143		7/50 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595833
Domainoid	1	1.000	47	1.000	Domainoid score	I12036
eggNOG	1	0.900	-	-		E1_28PXY
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5092
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380911at33208
OrthoFinder	1	1.000	-	-		FOG0006849
OrthoInspector	1	1.000	-	-		oto39940
orthoMCL	1	0.900	-	-		OOG6_108536
Panther	1	1.100	-	-	LDO	PTHR15079
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5112
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.790