DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myd88 and AgaP_AGAP012385

DIOPT Version :9

Sequence 1:	NP_001260821.1	Gene:	Myd88 / 35956	FlyBaseID:	FBgn0033402	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	XP_551799.2	Gene:	AgaP_AGAP012385 / 3291574	VectorBaseID:	AGAP012385	Length:	1353	Species:	Anopheles gambiae

Alignment Length:	167	Identity:	41/167 - (24%)
Similarity:	71/167 - (42%)	Gaps:	39/167 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 RYNACVLYAEADIDH---------------------ATEIMNNLESERYNLRLFLRHRDMLMGVP 285
            ::...:.|..||||.                     |.|:...||:|..:.:|.|.:||..:|..
Mosquito  1060 KFGVRLFYRNADIDKNERDKLFDAFISYSSKDEAFVAEELAPMLENEDPSYKLCLHYRDFPVGAY 1124

  Fly   286 FEHVQLSHFMATRCNHLIVVLTEEFLRSPENTYLVNFTQKIQIENHTRKIIPILYKTDMHIPQ-- 348
            .....|....::|  ..|:||:|.|::|....:.........:.:..|::|.||..   .:||
Mosquito  1125 IADNILQAVESSR--RTIMVLSENFIKSEWCRFEFKSAHHQVLRDRRRRLIVILLG---EVPQKD 1184

  Fly   349 ---TLGIY----THIKYAGDSKLFNFWDKLARSLHDL 378
               .:.:|    |:::: || ||  ||:||..:|.|:
Mosquito  1185 LDPDIRLYLKTNTYLQW-GD-KL--FWEKLRFALPDV 1217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myd88	NP_001260821.1	DD	90..172	CDD:301326
Myd88	NP_001260821.1	TIR_2	242..375	CDD:304906	39/162 (24%)
AgaP_AGAP012385	XP_551799.2	leucine-rich repeat	73..98	CDD:275380
		leucine-rich repeat	99..122	CDD:275380
		LRR_RI	<118..321	CDD:238064
		leucine-rich repeat	123..153	CDD:275380
		leucine-rich repeat	154..177	CDD:275380
		leucine-rich repeat	181..211	CDD:275380
		LRR_8	210..270	CDD:290566
		leucine-rich repeat	214..235	CDD:275380
		leucine-rich repeat	236..259	CDD:275380
		LRR_8	259..318	CDD:290566
		leucine-rich repeat	260..283	CDD:275380
		leucine-rich repeat	284..307	CDD:275380
		leucine-rich repeat	308..379	CDD:275380
		LRR_8	380..438	CDD:290566
		leucine-rich repeat	380..403	CDD:275380
		leucine-rich repeat	404..427	CDD:275380
		LRR_RI	421..651	CDD:238064
		leucine-rich repeat	428..450	CDD:275380
		LRR_8	449..509	CDD:290566
		leucine-rich repeat	451..474	CDD:275380
		leucine-rich repeat	475..496	CDD:275380
		LRR_8	497..556	CDD:290566
		leucine-rich repeat	499..522	CDD:275380
		leucine-rich repeat	523..543	CDD:275380
		leucine-rich repeat	546..567	CDD:275380
		leucine-rich repeat	568..592	CDD:275380
		leucine-rich repeat	593..613	CDD:275380
		leucine-rich repeat	615..638	CDD:275380
		leucine-rich repeat	639..658	CDD:275380
		leucine-rich repeat	703..739	CDD:275380
		leucine-rich repeat	792..814	CDD:275378
		LRR_8	794..849	CDD:290566
		leucine-rich repeat	815..838	CDD:275378
		LRR_8	837..897	CDD:290566
		leucine-rich repeat	839..862	CDD:275378
		leucine-rich repeat	863..886	CDD:275378
		TIR	1081..1216	CDD:214587	35/143 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910