Protein Alignment Myd88 and Il1rap

DIOPT Version :9

• Sequence 1: NP_001260821.1
• Gene: Myd88 / 35956
• FlyBaseID: FBgn0033402
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_038943965.1
• Gene: Il1rap / 25466
• RGDID: 2893
• Length: 697
• Species: Rattus norvegicus
• Alignment Length: 366
• Identity: 67/366 - (18%)
• Similarity: 127/366 - (34%)
• Gaps: 108/366 - (29%)

  Fly   216 NITVGQSVQILSDEDQRCVQM-------GQPLPRYNAC-VLYAEADIDHATEIMNNLESERYNLR 272
            :||:.:||...|.||:...|:       .:.|.|...| ...||.:.:.|.::...:...||.:.
  Rat   307 DITINESVSYSSTEDETRTQILSIKKVTPEDLKRNYVCHARNAEGEAEQAAKVKQKVIPPRYTVE 371

  Fly   273 LFLRHRDMLMGVPFEHVQLSHFMATRCNHLIVVLTEEFLRSPENTYLVNFTQKIQIENHTRKIIP 337
            |                 ...|.||  ..|:|||..        .|.|.:.:.:
  Rat   372 L-----------------ACGFGAT--VFLVVVLIV--------VYHVYWLEMV----------- 398

  Fly   338 ILYKTDMHIPQTLGIYTHIKYAGDSKLFNFWDKLARSLHDLDAFSIYSTRQVQTPSPVEESAPRV 402
            :.|:......:|:         .|.|.::.:...||:..: :.|.:.:.|.|     :|...
  Rat   399 LFYRAHFGTDETI---------LDGKEYDIYVSYARNAEE-EEFVLLTLRGV-----LENEF--- 445

  Fly   403 TTPSIRIQINDKDVTDMPNYNSCK-----VPEAETTIVSVSGD---------------------- 440
               ..::.|.|:|  .:|..|:.:     :..:...||.:|.|
  Rat   446 ---GYKLCIFDRD--SLPGGNTVEAVFDFIQRSRRMIVVLSPDYVTEKSISMLEFKLGVMCQNSI 505

  Fly   441 -TGSPLPEHKPKKKDR---FLRRITHSF----GKTARSDGAS-GKTLRHAHSVSTINVTERERTL 496
             |...:.|::|.::..   ...:.:.||    |:.::..|:. .|.||.|..:.:::.:......
  Rat   506 ATKLIVVEYRPLEQPHPGIMQLKESVSFVSWKGEKSKHSGSKFWKALRLALPLRSLSASSGWNES 570

  Fly   497 SASSSNISTTSESKKSFIKWQPNILKKALFSRSSSKLQTPG 537
            .:|.|:||.....::|.:|..|.:...   .|.|.....||
  Rat   571 CSSQSDISLDHVQRRSRLKEPPELQSS---ERVSGAAPAPG 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myd88	NP_001260821.1	DD	90..172	CDD:301326
		TIR_2	242..375	CDD:304906	23/133 (17%)
Il1rap	XP_038943965.1	Ig1_IL1R_like	37..144	CDD:409584
		Ig strand B	55..59	CDD:409584
		Ig strand C	79..83	CDD:409584
		Ig strand E	109..113	CDD:409584
		Ig strand F	123..128	CDD:409584
		Ig strand G	136..139	CDD:409584
		Ig	155..247	CDD:416386
		Ig strand A	157..162	CDD:409353
		Ig strand A	157..162	CDD:409353
		Ig strand B	168..172	CDD:409353
		Ig strand B	168..172	CDD:409353
		Ig strand C	186..191	CDD:409353
		Ig strand C	186..191	CDD:409353
		Ig strand C'	194..196	CDD:409353
		Ig strand C'	194..196	CDD:409353
		Ig strand D	201..205	CDD:409353
		Ig strand D	201..205	CDD:409353
		Ig strand E	207..212	CDD:409353
		Ig strand E	207..212	CDD:409353
		Ig strand F	221..230	CDD:409353
		Ig strand F	221..230	CDD:409353
		Ig strand G	233..246	CDD:409353
		Ig strand G	233..246	CDD:409353
		Ig3_IL1RAP	255..361	CDD:409525	14/53 (26%)
		Ig strand B	274..278	CDD:409525
		Ig strand C	291..295	CDD:409525
		Ig strand E	326..330	CDD:409525	1/3 (33%)
		Ig strand F	341..346	CDD:409525	1/4 (25%)
		Ig strand G	353..356	CDD:409525	0/2 (0%)
		TIR	416..559	CDD:214587	26/156 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910