DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myd88 and il18rap

DIOPT Version :9

Sequence 1:	NP_001260821.1	Gene:	Myd88 / 35956	FlyBaseID:	FBgn0033402	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	XP_002934549.3	Gene:	il18rap / 100491212	XenbaseID:	XB-GENE-480054	Length:	564	Species:	Xenopus tropicalis

Alignment Length:	155	Identity:	33/155 - (21%)
Similarity:	68/155 - (43%)	Gaps:	29/155 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   243 YNACVLYAEADID--------------HATEIMNNLESERYNLRLFLRHRDMLMGVPFEHVQLSH 293
            ::|.|.||:.:.|              .||:.:.::..::|:.:|.|..||:|.|..:  |:...
Frog   397 FDAFVSYAKHNSDFHEETFEDSHDEEVFATQFLPSVLEDKYHFKLCLLERDILPGGAY--VEDVV 459

  Fly   294 FMATRCNHLIVVLTEEFLRSPENTYLVNFTQKIQIENHTRKIIPIL---YKTDMHIP----QTLG 351
            .:..|...||.:|::.::.|| :.:.:.......:|....|:|.|.   :|....:|    :.|.
Frog   460 KIIKRSRRLIAILSQRYITSP-SVFELQAAITCTLEEEPIKLILIQLSPFKEPKSLPHIVKKALN 523

  Fly   352 IYTHIKYAGDSKL-----FNFWDKL 371
            ....:::.|:|..     ..||:|:
Frog   524 ALPTVEWKGNSDYSPSIDTKFWNKV 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myd88	NP_001260821.1	DD	90..172	CDD:301326
Myd88	NP_001260821.1	TIR_2	242..375	CDD:304906	33/155 (21%)
il18rap	XP_002934549.3	Ig	33..120	CDD:416386
		Ig strand A'	37..41	CDD:409353
		Ig strand B	45..50	CDD:409353
		Ig strand C	64..70	CDD:409353
		Ig strand C'	79..81	CDD:409353
		Ig_6	85..128	CDD:408247
		Ig strand D	88..92	CDD:409353
		Ig strand E	94..98	CDD:409353
		Ig strand F	107..115	CDD:409353
		Ig	<160..225	CDD:416386
		Ig strand C	163..168	CDD:409353
		Ig strand C'	171..173	CDD:409353
		Ig strand D	178..182	CDD:409353
		Ig strand E	187..192	CDD:409353
		Ig strand F	201..210	CDD:409353
		Ig strand G	213..225	CDD:409353
		Ig	234..339	CDD:416386
		Ig strand A	234..237	CDD:409353
		Ig strand A'	245..249	CDD:409353
		Ig strand B	251..260	CDD:409353
		Ig strand C	269..274	CDD:409353
		Ig strand C'	282..284	CDD:409353
		Ig strand D	292..300	CDD:409353
		Ig strand F	321..327	CDD:409353
		Ig strand G	331..337	CDD:409353
		TIR	415..552	CDD:396246	28/137 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910