DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cog6 and AT1G31780

DIOPT Version :9

Sequence 1:	NP_724783.1	Gene:	Cog6 / 35953	FlyBaseID:	FBgn0033401	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_174458.2	Gene:	AT1G31780 / 840065	AraportID:	AT1G31780	Length:	680	Species:	Arabidopsis thaliana

Alignment Length:	688	Identity:	203/688 - (29%)
Similarity:	343/688 - (49%)	Gaps:	94/688 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 IQKRVNKILEARLESDKDTLDALSGLSTFFTENTLQNRRNLRSQIEHRSVGINENFLKAFRQVKL 78
            :.:::.|:|:.|.:| .|.:.:|:.||:|:.||:...||||||.||.|::.||..||.|....::
plant    11 LSRKLKKVLDCRTDS-PDLVASLNALSSFYDENSAHARRNLRSTIEKRALQINSEFLNAADSTQI 74

  Fly    79 SLDAVCEDLDTMATSVETMKSDLETSKALTKDLIKQTNTMQRERDRLEVHKQIAQAFLARFQLSG 143
            :||.|.|:::.:|...:.:.:.|.:|.|.|.|:|..|..:::|.:.....::|...||..:|||.
plant    75 ALDRVEEEVNALADCCDKIAAALSSSAATTSDIISTTERLKQELEVTTQRQEIVNCFLRDYQLSN 139

  Fly   144 AEHQLLYGAAKDAPIVADFFRVLDRVQSIHADCRLLMQCGYQTAAIDIMEEMTLHQEGALERLYR 208
            .|.:    |.::..:..:||:.|..||.||::|:||::..:|.|.:::|:.|.::||||.|||.|
plant   140 EEIK----ALREDELNENFFQALSHVQEIHSNCKLLLRTHHQRAGLELMDMMAVYQEGAYERLCR 200

  Fly   209 WTQNHCRSL---ENNEIGPLIVEAMSRLQDRPVLFKYVIDEYAIARRAVLVRQFIEALTEGGPGG 270
            |.|..||.|   :|.|:..|:..|:..|::|||||||..:|....|...|.|:||.|||.|||||
plant   201 WVQAECRKLGDTDNPEVSELLRTAVRCLKERPVLFKYCAEEVGNLRHNALFRRFISALTRGGPGG 265

  Fly   271 NPKPIELHAHDPKRYIGDMFAWLHQSIPTEKENLSLLFKKCDKQDISDQLQN------------- 322
            .|:|||:|||||.||:|||..||||::.:|:|.:..|| ..|..|.....:|
plant   266 MPRPIEVHAHDPLRYVGDMLGWLHQALASERELVHALF-DIDSADHQSNAKNTSENIALKAGESD 329

  Fly   323 ---ALGYIADGVCHPLKVRVETILQAEKDTIVLFTISNLLRFYQQIMRQVV-QGGSLEECLVELQ 383
               .|..|.:|||.|.|||||.:||::...|:.:.::|.|.||...:..:: :..:|...:..::
plant   330 FTFVLDRIFEGVCRPFKVRVEQVLQSQPSLIISYKLTNTLEFYSYTISDLLGRDTALCNTIGMVK 394

  Fly   384 KSSEQIYLGALAAQVRSVLQRPSGGSGLALEPPQR-DLVPPPSVARLLNMLKEIL----SVATMV 443
            .::::.:...|..:...:|:.|         ||.. ||.|||:|...:::..||:    |:....
plant   395 DAAQKTFFDILKTRGEKLLRYP---------PPVAVDLSPPPAVREGVSLTLEIIENYNSMMVSA 450

  Fly   444 DGRQADITKIVSCVIDPLLQSVQESA-AH--------------------LPTVD----------- 476
            .|.:.....::|.::||:::..:::| ||                    |.:||
plant   451 SGEKPAFDPVLSALLDPIIKMCEQAAEAHKSKKSGQLPRRSRTSSDSSQLTSVDALLSSSPSPPQ 515

  Fly   477 -----MGVYLLNCLHHMQSSLAVYEYMDERVERLQAQSDAQLDTLTSEQASSLVANLNLGPIYAI 536
                 ..::|:|||..:|..|..::...:.|..:....:..::.|...:..:|:....|.....|
plant   516 NNETPSKIFLINCLCAIQQPLLRHDVASQYVTNIGLMIENHINLLVQNEVDTLLHKCGLSDKMQI 580

  Fly   537 LQSNQSKIE------------TNLLKIFMSKMDAFLELPDVLLLPQVQLIMSSSHRAAVQKRSFN 589
            .:|:.|::.            :..||.|..     |.|.....||:.:.|.....|:....|...
plant   581 FRSSTSELPLSERQDTSPAMLSECLKAFFG-----LVLGSEGSLPEFEQIQVPKLRSEACVRVAK 640

  Fly   590 VIVAIYKQIYERVHDPANGFEQPEQLLHRTPEQVAHIL 627
            .:...|:.||:.|.|..||:..|:.|....|:|:..||
plant   641 TLAEAYEVIYQAVTDQQNGYPDPKSLARHPPDQIRTIL 678

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cog6	NP_724783.1	COG6	47..627	CDD:215018	190/653 (29%)
AT1G31780	NP_174458.2	COG6	31..674	CDD:368895	195/661 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	296	1.000	Domainoid score	I347
eggNOG	1	0.900	-	-		E1_KOG3758
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10802
Inparanoid	1	1.050	305	1.000	Inparanoid score	I764
OMA	1	1.010	-	-		QHG54363
OrthoDB	1	1.010	-	-		D1370285at2759
OrthoFinder	1	1.000	-	-		FOG0005102
OrthoInspector	1	1.000	-	-		oto3482
orthoMCL	1	0.900	-	-		OOG6_102906
Panther	1	1.100	-	-	LDO	PTHR21506
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4130
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840