Protein Alignment Cog6 and Cog6

DIOPT Version :10

• Sequence 1: NP_724783.1
• Gene: Cog6 / 35953
• FlyBaseID: FBgn0033401
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001004262.1
• Gene: Cog6 / 310411
• RGDID: 1303283
• Length: 657
• Species: Rattus norvegicus
• Alignment Length: 643
• Identity: 263/643 - (40%)
• Similarity: 416/643 - (64%)
• Gaps: 28/643 - (4%)

  Fly     3 STQEKPEELDRIQKRVNKILEARLESDKDTLDALSGLSTFFTENTLQNRRNLRSQIEHRSVGINE 67
            :|..:|.  :.:.::::||||.|||:||:.|:||..||.||.||:|:.|||||..||.||:.|||
  Rat    26 ATPAQPN--NPLSRKLHKILETRLENDKEMLEALKALSAFFVENSLRTRRNLRGDIERRSLAINE 88

  Fly    68 NFLKAFRQVKLSLDAVCEDLDTMATSVETMKSDLETSKALTKDLIKQTNTMQRERDRLEVHKQIA 132
            .|:..|:.||..|:::.||:..|::..:.|.|.|:.:|..|:|||.:|..:|.|..|||:..|:|
  Rat    89 EFVSIFKDVKEELESINEDVQAMSSCCQDMTSRLQAAKEQTQDLIVKTTKLQAENQRLEIRAQVA 153

  Fly   133 QAFLARFQLSGAEHQLLYGAAKDAPIVADFFRVLDRVQSIHADCRLLMQCGYQTAAIDIMEEMTL 197
            .|||::|||:..|..||.| .:..|:..|||:.|.||:.||.|.::|::...|||.::|||:|.|
  Rat   154 DAFLSKFQLTSDEMTLLRG-TRGGPVTEDFFKALGRVKQIHNDVKVLLRTNQQTAGLEIMEQMAL 217

  Fly   198 HQEGALERLYRWTQNHCRSL--ENNEIGPLIVEAMSRLQDRPVLFKYVIDEYAIARRAVLVRQFI 260
            .||.|.||||||.|:.||:|  |:.::..::.:||..|||||||:||.:||:..|||:.:||.||
  Rat   218 LQETAYERLYRWAQSECRALTQESCDVSAVLTQAMEALQDRPVLYKYTLDEFGTARRSTVVRGFI 282

  Fly   261 EALTEGGPGGNPKPIELHAHDPKRYIGDMFAWLHQSIPTEKENLSLLFKKCDKQDISDQLQNALG 325
            :|||.|||||.|:|||:|:|||.||:|||.|||||:..:|||:|..|.|....|.:.:.:|..:|
  Rat   283 DALTRGGPGGTPRPIEMHSHDPLRYVGDMLAWLHQATASEKEHLEALLKHVTAQGVKENIQEVVG 347

  Fly   326 YIADGVCHPLKVRVETILQAEKDTIVLFTISNLLRFYQQIMRQVV--QGGSLEECLVELQKSSEQ 388
            :|.:|||.|||||:|.::.||...::|:.|||||:||...:..:|  ...:|...:.|:...|::
  Rat   348 HITEGVCRPLKVRIEQVILAEPGAVLLYKISNLLKFYHHTISGIVGNSAATLLTTIEEMHLLSKK 412

  Fly   389 IYLGALAAQVRSVLQRPSGGSGLALEPPQRDLVPPPSVARLLNMLKEIL----SVATMVDGRQAD 449
            |:..:|:.....::.:      :.|.||  ||.|..::::.|.:|:::|    |....:|.||||
  Rat   413 IFFSSLSLHANKLMDK------IELPPP--DLGPSSALSQTLTLLRDVLASHDSSVVPLDARQAD 469

  Fly   450 ITKIVSCVIDPLLQSVQESAAHLPTVDMGVYLLNCLHHMQSSLAVYEYMDERVERLQAQSDAQLD 514
            ..:::|||:|||||....||::|.|.||..:::|.|:.|:::||::|:.|.|:|.||.|.:|.||
  Rat   470 FVQVLSCVLDPLLQMCTVSASNLGTADMATFMVNSLYMMKTTLALFEFTDRRLEMLQFQIEAHLD 534

  Fly   515 TLTSEQASSLVANLNLGPIYAILQ---------SNQSKIETNLLKIFMSKMDAFLELPDVLLLPQ 570
            ||.:||||.::..:.|..||..:|         ::...:::..||..|::.|.:|..||.||:||
  Rat   535 TLINEQASYVLTRVGLSYIYNTIQQHRPDQGSLASMPNLDSVALKAAMAQFDRYLSAPDHLLMPQ 599

  Fly   571 VQLIMSSSHRAAVQKRSFNVIVAIYKQIYERVHDPANGFEQPEQLLHRTPEQVAHILT 628
            :..::|::.:..:.|:|..::...|.:::..|.:|.|.::.||.:|||:||||..:|:
  Rat   600 LNSLLSATVKEQIIKQSTELVCRAYGEVHAAVMNPVNAYKDPESILHRSPEQVKTLLS 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cog6	NP_724783.1	COG6	47..627	CDD:215018	242/596 (41%)
Cog6	NP_001004262.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	14..36		2/9 (22%)
		COG6	56..652	CDD:461904	252/613 (41%)