DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2063 and Sap30bp

DIOPT Version :9

Sequence 1:	NP_610475.1	Gene:	CG2063 / 35952	FlyBaseID:	FBgn0033400	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_065229.2	Gene:	Sap30bp / 57230	MGIID:	1927479	Length:	308	Species:	Mus musculus

Alignment Length:	353	Identity:	116/353 - (32%)
Similarity:	173/353 - (49%)	Gaps:	89/353 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LASLT--AQYTDSENEGDASPDSQNSTASLVIIPPKRPTPTPTKQDEESKRSKEKKKKRAKKVRR 66
            |:||.  |:|:|.|::|:...|:....                        ::||
Mouse     8 LSSLAIYAEYSDPESDGETGVDAVGGA------------------------TEEK---------- 38

  Fly    67 LVSYQDDTLISDE--DEDRAAASSSEEESSSGDESNSSNSQSEDS----PKAKD-KSNAGSGSKD 124
                  ..|:||.  ::|.:.....|:.....::.||..|:.:||    |:|.| |.|..:..:|
Mouse    39 ------GGLVSDAYGEDDFSRPGGDEDGYEEEEDENSKQSEDDDSETEKPEADDPKDNTEAEKRD 97

  Fly   125 GDTPMEVDEEPACFPVEERTAESYEKDAKYAKYKFQLPPEPKGKPSAELVAKITKMYTKMNQTNM 189
               |.|:            .|...|:....:..:.::||||.|:.|..|..||.|:|.:..:..|
Mouse    98 ---PQEL------------VASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGM 147

  Fly   190 DMNRVIQDRKEFRNPSIYDKLISFCDINEFGTNYPPEIYDPLQWGEESYYESLAAVQKTEMVKRQ 254
            |||.:||.:|||||||||:|||.||.|:|.|||||.:::||..|.|:||||:||..||.||.|.:
Mouse   148 DMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLE 212

  Fly   255 KDRKDMDKVE---------------QATALARKVEEEAKKRKSKWDQPAPSSTVVK-------TT 297
            |.:|:..|:|               .:|:.|.....:|:|||||||...|.:|:.:       .|
Mouse   213 KAKKERTKIEFVTGTKKGTTTNATATSTSTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTAT 277

  Fly   298 LPA---LTTTVTGTKGTVISAFGSLPKK 322
            |||   :||:.:|:|.|||||.|::.||
Mouse   278 LPAVVTVTTSASGSKTTVISAVGTIVKK 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2063	NP_610475.1	HCNGP	161..247	CDD:285109	48/85 (56%)
Sap30bp	NP_065229.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	15..101		25/128 (20%)
Sap30bp	NP_065229.2	HCNGP	119..205	CDD:285109	48/85 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848268
Domainoid	1	1.000	115	1.000	Domainoid score	I6025
eggNOG	1	0.900	-	-		E1_KOG2959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4126
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1557444at2759
OrthoFinder	1	1.000	-	-		FOG0006099
OrthoInspector	1	1.000	-	-		oto93512
orthoMCL	1	0.900	-	-		OOG6_104160
Panther	1	1.100	-	-	LDO	PTHR13464
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R769
SonicParanoid	1	1.000	-	-		X5841
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790