DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2063 and sap30bp

DIOPT Version :9

Sequence 1:	NP_610475.1	Gene:	CG2063 / 35952	FlyBaseID:	FBgn0033400	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_955859.2	Gene:	sap30bp / 321738	ZFINID:	ZDB-GENE-030131-457	Length:	304	Species:	Danio rerio

Alignment Length:	347	Identity:	130/347 - (37%)
Similarity:	173/347 - (49%)	Gaps:	79/347 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AALASLTAQYTDSENEGDASPDSQNSTASLVIIPPKRPTPTPTKQDEESKRSKEKKKKRAKKVRR 66
            |.::||.|...|||.:.|...|.|.|          |...:.:..::|..|.:|..:|
Zfish     8 ALISSLAAYGDDSEQDSDPDTDDQES----------RGLVSASYGEDEVSRVEEAYEK------- 55

  Fly    67 LVSYQDDTLISDEDEDRAAASSSEEESSSGDESNSSNSQSEDSPKAKDKSNAGSGSKDGDTPMEV 131
             .|..:|   ||||..|   :|.||||.||        :.:|..|                  ||
Zfish    56 -PSENED---SDEDSTR---NSDEEESDSG--------RIQDDVK------------------EV 87

  Fly   132 DEEPACFPVEERTAESYEKDAKYAKYKFQLPPEPKGKPSAELVAKITKMYTKMNQTNMDMNRVIQ 196
            .|.....| .|..|:..||....:..:.::||||.|:.|:.|..||.|:|.:..|.:.|.|..||
Zfish    88 QEVEVKDP-NELVAQFSEKVRNMSPDEIRIPPEPPGRCSSHLQEKIFKLYERKLQGDFDTNSHIQ 151

  Fly   197 DRKEFRNPSIYDKLISFCDINEFGTNYPPEIYDPLQWGEESYYESLAAVQKTEMVKRQKDRKDMD 261
            .:|||||||||:|||.||||:|.|||||.:::||..|.|:||||:||..||.||.|.:|.:|:..
Zfish   152 KKKEFRNPSIYEKLIQFCDIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKVEMDKLEKAKKEKT 216

  Fly   262 KVE-----------QATALARKV----EEEAKKRKSKWD--------QPAPSSTVVKTTLP---A 300
            |:|           .|.|||...    ..:|:|||||||        |||..:|.  .|||   :
Zfish   217 KIEFVTGTKKGTTTNAAALATNTTATSSTDAQKRKSKWDSAVPVTLAQPALLTTT--ATLPGVVS 279

  Fly   301 LTTTVTGTKGTVISAFGSLPKK 322
            :|||.:|||.|||||.|::.||
Zfish   280 VTTTASGTKTTVISAVGTIHKK 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2063	NP_610475.1	HCNGP	161..247	CDD:285109	48/85 (56%)
sap30bp	NP_955859.2	PHA02664	<23..97	CDD:177447	29/124 (23%)
sap30bp	NP_955859.2	HCNGP	116..202	CDD:285109	48/85 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593684
Domainoid	1	1.000	115	1.000	Domainoid score	I5992
eggNOG	1	0.900	-	-		E1_KOG2959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4022
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1557444at2759
OrthoFinder	1	1.000	-	-		FOG0006099
OrthoInspector	1	1.000	-	-		oto40918
orthoMCL	1	0.900	-	-		OOG6_104160
Panther	1	1.100	-	-	LDO	PTHR13464
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R769
SonicParanoid	1	1.000	-	-		X5841
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.790