DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pkn and gwl

DIOPT Version :9

Sequence 1:	NP_001097237.1	Gene:	Pkn / 35950	FlyBaseID:	FBgn0020621	Length:	1501	Species:	Drosophila melanogaster
Sequence 2:	NP_524860.2	Gene:	gwl / 45969	FlyBaseID:	FBgn0260399	Length:	846	Species:	Drosophila melanogaster

Alignment Length:	219	Identity:	70/219 - (31%)
Similarity:	117/219 - (53%)	Gaps:	20/219 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly  1112 AKAAAAASV---YSPSSSTTSNSNQQQQQQRRNVARGLQYRESGGLETGRAGKQPPNAGMLSMDN 1173
            |.|.:.:.|   |.....|.|..:.:|...:.|:.            |.:......||.:.::.:
  Fly     4 ADATSQSDVHIDYKTPKKTHSLIDSEQLLDKINIL------------TTKPENHSQNAKLPTIKD 56

  Fly  1174 FRLLSVLGRGHFGKVILSQLRSNN-QYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFL 1237
            |.::..:.||.||||.|....::: :.:|||.::|.::|.::.|..:::|:....::   |..|.
  Fly    57 FVIIKPISRGAFGKVFLGYKNNDSKRLFAIKVMRKSEMINKNMVSQVITERNALALS---RSQFC 118

  Fly  1238 VNLYSCFQTEQHVCFVMEYAAGGDLMMHIHT-DVFLEPRAVFYAACVVLGLQYLHENKIIYRDLK 1301
            |:|:...|:..:|..||||..||||...:.. ..|.||.|.||.|.:|:.|||||::.|::||:|
  Fly   119 VSLFYSLQSLSYVYLVMEYMVGGDLKSLLAMFGYFDEPTARFYVAEMVMALQYLHQHGIVHRDIK 183

  Fly  1302 LDNLLLDTEGYVKIADFGLCKEGM 1325
            .||:||.:.|:||:.||||.|..|
  Fly   184 PDNMLLSSSGHVKLTDFGLSKIDM 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkn	NP_001097237.1	HR1_PKN_1	131..194	CDD:212012
		HR1_PKN_2	243..309	CDD:212013
		HR1_PKN_3	340..414	CDD:212015
		C2	530..611	CDD:301316
		STKc_PKN	1174..1499	CDD:270741	59/154 (38%)
		S_TKc	1174..1433	CDD:214567	59/154 (38%)
gwl	NP_524860.2	STKc_MASTL	52..>255	CDD:270761	59/159 (37%)
		S_TKc	57..>205	CDD:214567	57/150 (38%)
		PKc_like	<655..835	CDD:304357
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100