DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkn and CG32944

DIOPT Version :9

Sequence 1:	NP_001097237.1	Gene:	Pkn / 35950	FlyBaseID:	FBgn0020621	Length:	1501	Species:	Drosophila melanogaster
Sequence 2:	NP_788574.3	Gene:	CG32944 / 40560	FlyBaseID:	FBgn0052944	Length:	576	Species:	Drosophila melanogaster

Alignment Length:	351	Identity:	105/351 - (29%)
Similarity:	177/351 - (50%)	Gaps:	42/351 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1169 LSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMR 1233
            ::.|:|::|..:|:|.||||.:.|.|.....||:|.:.:.....|..:..::.|   .|:.:::.
  Fly   146 INFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKE---VELLSSLE 207

  Fly  1234 HPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLG--LQYLHENKII 1296
            |||||||:..||.|:.:..|.:...||||..|:...|....::|....| .||  |:||..|:::
  Fly   208 HPFLVNLWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVALLVC-ELGSALEYLQANRVV 271

  Fly  1297 YRDLKLDNLLLDTEGYVKIADFGLC----KEGMGFGDRTGTFCGTPEFLAPEV----LTETS-YT 1352
            :||:|.||:|||..|:..:.||.:.    |..:..     :..||..::||||    |.|.: |:
  Fly   272 HRDIKPDNILLDDAGHAHLTDFNIATRLQKNALAC-----SMSGTKPYMAPEVFLCALDEVAGYS 331

  Fly  1353 RAVDWWGLGVLIFEMLVGESPFPGDDEEEVFD--SIVNDEVRYPRFLSLEAIAVMRRLLRKNPER 1415
            ..||||.|||:.:||.....||.......:.:  :|:|..|.|||:.|...:.:::|||...|..
  Fly   332 YPVDWWSLGVVAYEMRGNIRPFVVHSNTPLAEIKNILNTPVHYPRYWSSNFVDLLQRLLSTYPGA 396

  Fly  1416 RLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFD-----EEFTSE----- 1470
            |:.:    .:::.:....|:|.:..:|.:|:||.:.|..:||    |.|     ||...|
  Fly   397 RIST----RQELHQTPMLRNIDFQRVLEKKIKPIYKPPEDHL----NCDPCLELEEMIVESRPLH 453

  Fly  1471 --KAQLTPPKEPRHLTEEEQLLFQDF 1494
              |.:|...:..:..::.|..|.::|
  Fly   454 KKKKRLAKQRSAQRDSDPETALVKEF 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkn	NP_001097237.1	HR1_PKN_1	131..194	CDD:212012
		HR1_PKN_2	243..309	CDD:212013
		HR1_PKN_3	340..414	CDD:212015
		C2	530..611	CDD:301316
		STKc_PKN	1174..1499	CDD:270741	104/346 (30%)
		S_TKc	1174..1433	CDD:214567	85/271 (31%)
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	85/272 (31%)
CG32944	NP_788574.3	S_TKc	151..405	CDD:214567	85/266 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100