Protein Alignment Pkn and dop

DIOPT Version :9

• Sequence 1: NP_001097237.1
• Gene: Pkn / 35950
• FlyBaseID: FBgn0020621
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_001261884.1
• Gene: dop / 39686
• FlyBaseID: FBgn0267390
• Length: 2139
• Species: Drosophila melanogaster
• Alignment Length: 1236
• Identity: 285/1236 - (23%)
• Similarity: 480/1236 - (38%)
• Gaps: 348/1236 - (28%)

  Fly   422 QQLKTELQIVQLSTSPAPVTYTSLQSGQAGILGGKP----YQSVSSLGRC---ASVTGKLEVRLL 479
            |.:.:|::.:.:|.|.:..:.:...:.....:.|.|    :.|.::|.|.   :|.:.::
  Fly    59 QSVASEIEAMSISDSASAESSSGATATATATMSGSPVPKRHLSTANLSRIRPQSSYSARV----- 118

  Fly   480 GCQDLLEDVPGRSRRDKDNNSSPGDLRSFVKGVTSRSSSKSYSVKDETSIEIMAVIKLDNITVGQ 544
                |:.|       |.|..::     :....:.:.|||.:.|||..:.:|::..... .:::|.
  Fly   119 ----LIFD-------DSDQEAA-----AAAAALAAASSSCNSSVKSCSGLELLPTSPA-KLSIGN 166

  Fly   545 TSWKQCSQQAWDQRFSIDLDRS---------------------RELEIGVYWRDWRSLCAV---- 584
            .|....|...     :::|.:|                     |::.   |.:...||.||
  Fly   167 DSTNGSSMMR-----NLNLTKSSSGGLSGSSSSLHSRGYTALLRKIS---YQQHTNSLRAVSGET 223

  Fly   585 -KVLRLEEFIDDVRHGMALQLEP--QGLLFAEVKFLNPMISQKPKLRRQRMIFNRQQAKNISRAK 646
             .:||:       ||....:..|  .|..|.. :...|:..|.|......:     ...||||:.
  Fly   224 SNLLRM-------RHSSLGKSAPCLTGNYFRH-ELTAPLPVQPPGFGASPL-----GGHNISRSG 275

  Fly   647 QMNINVATWGRLLKRNAPNHVH----MGSAGSGSSLTGSSPMVV-----------------GGSR 690
                :.|..| |.|.:..:|:|    .||||.|:...|.|...|                 ||||
  Fly   276 ----SCAGIG-LAKHHHHHHLHGVVMRGSAGGGAGSGGGSSSGVAHHRLSLVTNSAAVAAAGGSR 335

  Fly   691 DSESPISRTP-SSDALVEPEPY---------------------------------TPGEQAQNLE 721
             :.||.|.:| .|..|..|.|:                                 |||....:.:
  Fly   336 -THSPYSASPVDSPRLNSPMPFAFAPIKRIASCRGVVADGRRWSVASLPSSGYGTTPGSSNLSSQ 399

  Fly   722 FDPDAGINE--HVETPGEYPDPAASGLSG---MRPLSMH-------MQGIS--VLPPESPPVAT- 771
            .....|:|:  |...||.....||:..:|   ...|..|       :..:|  .|.|: ||..|
  Fly   400 CSSQEGLNQLAHNIPPGVQEADAAAVAAGACCAEHLKQHCPKHCALLLAVSQKQLTPQ-PPKPTQ 463

  Fly   772 -----------------------------GAAGRPNTLSLQMPGASKGQVIQGGRTAAPTTAP-- 805
                                         |||...:  |....|:|..||  |||     .:|
  Fly   464 LQPQKSMTAACVNCCAELSVTCGGQQAGGGAANGGS--SANSSGSSAMQV--GGR-----MSPYF 519

  Fly   806 -PPPPVLKATSTTPILDQEL--QDALHEFDFLSDLDSRPTTLRRLLKEQKMAL-----DAGALEN 862
             |....|.:.|.:||:|.|:  .:.|::..|..........|:..:.|.|.|.     |:..:..
  Fly   520 RPRSRSLSSPSRSPIVDNEIAVMNTLYKERFPKATQQMEERLKLFINENKSAACNSFRDSQPIVR 584

  Fly   863 LLLQQQQTEQQALQQRQRQEQLRLQQFQEAQRQAILDLCVKQREPAEQTSPTLANQTPTFPPLAS 927
            .:..|.....:....:...:.:..|.|.|.. :.:..|.|:.:|.:.:.:..|
  Fly   585 FVHHQVLEMARDCLHKSEAKLITSQYFYELS-ENLERLLVETKEKSPEAAAEL------------ 636

  Fly   928 NQIMPSL---NARP-----CQSQSPNHNEFQLQPQPPHPAQKPT---------------NPEPPS 969
            |.::..|   .:||     |....|......|:....|....|.               |.:|.:
  Fly   637 NGVIKKLLLIISRPARLLECLEFDPQEFYELLEAAEGHAKAMPVIKADIPQYIIHKLGLNRDPIA 701

  Fly   970 AVEQQLHRPVLILPPVVLLGGREEDRSVPPSPLVEYPEDDDEYLYRGSNENLGTRLHSSHSSSAG 1034
            .::|:|               ||..:.......|     |.:.|:.|     |:.|.:|..:||.
  Fly   702 ELQQEL---------------RETQQMCSEQVTV-----DADPLHPG-----GSLLLNSPLTSAA 741

  Fly  1035 DRFCVEVIPQLGKLYVGSSQQQYAQQSSPIIQEPATPTIYGNSAAAGAPQFPQP-AQRQEKQPPQ 1098
                    .||..|.:.:........::...|.|.||.    :....||.|... :|..|::...
  Fly   742 --------KQLSSLALDAIAMDSGSGTATPQQPPQTPV----ATCDTAPSFALAISQMNEEKGGS 794

  Fly  1099 QQPIYANQYELNVAKAAAAASVYSPSSSTTSNSNQQQQQQRRNVARGLQYRESGGLETGRAGKQP 1163
            ...:...    :.:|.|.|..:...|::|.:.|..||...:.|
  Fly   795 SSAVGGG----SSSKVAGAEGITGGSAATATGSGAQQPSPQEN---------------------- 833

  Fly  1164 PNAGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEV 1228
                     :|.::.::..|.:|.|.|.:.::..|.:|:|.:.|.::|.|::||.:.:|:.|...
  Fly   834 ---------DFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSF 889

  Fly  1229 ANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGD---LMMHI---HTDVFLEPRAVFYAACVVLGL 1287
            |:   :||:|::|..|:|::|:|.||||..|||   |:.:|   ..|:     |.||.|..||.:
  Fly   890 AD---NPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADM-----ARFYFAETVLAV 946

  Fly  1288 QYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGM---------GFGD-RTGTFC-----GT 1337
            :|||...|::||||.||||:...|::|:.||||.|.|:         |:.| .|..|.     ||
  Fly   947 EYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGT 1011

  Fly  1338 PEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRF----LS 1398
            ||::||||:....|.:.||||.:|::::|.|:|..||.|:..||:|...|||::.:|..    :.
  Fly  1012 PEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQ 1076

  Fly  1399 LEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNF 1463
            .||..::.:||::||..||| ::..|.::|:..:|..:.|:.||.:|.:  |||.::|.:|.|.|
  Fly  1077 AEAKDIISQLLQQNPRDRLG-TQSGALEMKEHEYFLGMDWNSLLRQKAE--FVPQLSHDDDTSYF 1138

  Fly  1464 D 1464
            |
  Fly  1139 D 1139

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkn	NP_001097237.1	HR1_PKN_1	131..194	CDD:212012
		HR1_PKN_2	243..309	CDD:212013
		HR1_PKN_3	340..414	CDD:212015
		C2	530..611	CDD:301316	18/108 (17%)
		STKc_PKN	1174..1499	CDD:270741	115/316 (36%)
		S_TKc	1174..1433	CDD:214567	102/283 (36%)
dop	NP_001261884.1	DUF1908	344..702	CDD:286070	69/380 (18%)
		STKc_MAST	834..1115	CDD:270760	103/289 (36%)
		S_TKc	835..1110	CDD:214567	102/283 (36%)
		PDZ_signaling	1506..1587	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010