Protein Alignment Pkn and Rps6kb2

DIOPT Version :10

• Sequence 1: NP_001097237.1
• Gene: Pkn / 35950
• FlyBaseID: FBgn0020621
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_001010962.2
• Gene: Rps6kb2 / 361696
• RGDID: 1305144
• Length: 485
• Species: Rattus norvegicus
• Alignment Length: 333
• Identity: 136/333 - (40%)
• Similarity: 205/333 - (61%)
• Gaps: 16/333 - (4%)

  Fly  1174 FRLLSVLGRGHFGKVI-LSQLRSNN--QYYAIKALKKGDII--ARDEVESLLSEKRIFEVANAMR 1233
            |.||||||:|.:|||. :.:::..|  :.||:|.|:|..|:  |:|...: .:|:.|.|   :::
  Rat    67 FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHT-RAERNILE---SVK 127

  Fly  1234 HPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTD-VFLEPRAVFYAACVVLGLQYLHENKIIY 1297
            |||:|.|...|||...:..::|..:||:|..|:..: :|||..|.||.|.:.|.|.:||...|||
  Rat   128 HPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIY 192

  Fly  1298 RDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGV 1362
            ||||.:|::|:::|::|:.|||||||.:..|..|.|||||.|::|||:|....:.||||||.||.
  Rat   193 RDLKPENIMLNSQGHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEILVRIGHNRAVDWWSLGA 257

  Fly  1363 LIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDV 1427
            |:::||.|..||..::.::..|.|:..::..|.:|:.:|..:.::.|::||..|:|....||.||
  Rat   258 LMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDARDLAKKFLKRNPTHRIGGGPGDAADV 322

  Fly  1428 KKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEP--RHLTEEEQLL 1490
            ::..|||.|.|||||..:|.|||.|::...||||.||..||.:    ||...|  ..|:|.....
  Rat   323 QRHPFFRHINWDDLLAHRVDPPFRPSLQSEEDVSQFDVRFTRQ----TPVDSPDDTALSESANQA 383

  Fly  1491 FQDFSYTA 1498
            |..|:|.|
  Rat   384 FLGFTYVA 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkn	NP_001097237.1	HR1_PKN_1	131..194	CDD:212012
		HR1_PKN_2	243..309	CDD:212013
		HR1_PKN_3	340..414	CDD:212015
		C2	530..611	CDD:472691
		STKc_PKN	1174..1499	CDD:270741	136/333 (41%)
Rps6kb2	NP_001010962.2	STKc_p70S6K	70..392	CDD:270736	134/330 (41%)