DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkn and rskra

DIOPT Version :9

Sequence 1:	NP_001097237.1	Gene:	Pkn / 35950	FlyBaseID:	FBgn0020621	Length:	1501	Species:	Drosophila melanogaster
Sequence 2:	XP_005157500.1	Gene:	rskra / 101883587	ZFINID:	ZDB-GENE-130103-8	Length:	427	Species:	Danio rerio

Alignment Length:	328	Identity:	95/328 - (28%)
Similarity:	169/328 - (51%)	Gaps:	31/328 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly  1173 NFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFL 1237
            :.::|..:.:|.||.::..:..|..:.||:|.|.|..::....::.  |::.:. :...:|||||
Zfish    90 DLQILGFIAKGSFGPILKVKDVSKEETYAVKVLPKAAVLRHGVLQQ--SKEEVI-IQRQVRHPFL 151

  Fly  1238 VNLYSCFQTEQHVCFVMEYAAGGDLMMH-IHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLK 1301
            ::|..|:|::.::..:.:|.:.|||..: ....:|.|.....:||.:...|.:||...||:||:|
Zfish   152 LSLRDCWQSQSNLFIMCDYCSTGDLYTYWTLKGLFEETDVRVFAAELGSALGFLHNFGIIHRDVK 216

  Fly  1302 LDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFE 1366
            ::|:||..:|::::.||||.:. :..|:|..|.|||.:::|||||:...|:.|.|||.||:|::.
Zfish   217 MENILLTDKGHLRLTDFGLSRR-LERGERAFTICGTIQYMAPEVLSGGPYSHAADWWSLGILLYA 280

  Fly  1367 MLVGESPFPGDDEEEVFDSIVNDEV-RYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQ 1430
            :..||.|...:.:..|..|.|::.: ..|..||.....::..||.|.|.|||    |..|..:..
Zfish   281 LATGEFPLAAEVDHAVMLSRVSEGLYEMPVSLSPALAFLLIELLCKIPTRRL----RCLEHFQSH 341

  Fly  1431 AFFRSIVWDDLLLRKVKP--PFVPTINH------------LEDVSNFDEEFTSEKAQLTPPKEPR 1481
            .||..:.:|..||:: .|  |.:....|            |:.:.||:.:.      |..|..|.
Zfish   342 KFFHGMSFDSQLLQR-NPIEPILALKTHPDLRERSMRGLSLDLLQNFECDL------LNSPSTPT 399

  Fly  1482 HLT 1484
            .|:
Zfish   400 DLS 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkn	NP_001097237.1	HR1_PKN_1	131..194	CDD:212012
		HR1_PKN_2	243..309	CDD:212013
		HR1_PKN_3	340..414	CDD:212015
		C2	530..611	CDD:301316
		STKc_PKN	1174..1499	CDD:270741	95/327 (29%)
		S_TKc	1174..1433	CDD:214567	80/260 (31%)
rskra	XP_005157500.1	S_TKc	92..344	CDD:214567	80/259 (31%)
rskra	XP_005157500.1	STKc_AGC	97..344	CDD:270693	79/254 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0694
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900