DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkn and rskrb

DIOPT Version :9

Sequence 1:	NP_001097237.1	Gene:	Pkn / 35950	FlyBaseID:	FBgn0020621	Length:	1501	Species:	Drosophila melanogaster
Sequence 2:	XP_003200943.1	Gene:	rskrb / 100537227	ZFINID:	ZDB-GENE-120215-252	Length:	445	Species:	Danio rerio

Alignment Length:	336	Identity:	102/336 - (30%)
Similarity:	175/336 - (52%)	Gaps:	36/336 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly  1164 PNAGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEV 1228
            |:..:...::|::|..:.:|.||.::..:.:|..:.||:|.:.|.:|:....:|.  |::.:. |
Zfish    92 PHRIVPGQEHFQVLGYIAKGSFGPILKVKDKSKQKTYAVKVIPKSEILRLGVLEQ--SKEEVI-V 153

  Fly  1229 ANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMH-IHTDVFLEPRAVFYAACVVLGLQYLHE 1292
            ...:||||:.:|..|:||::|:..:.:|.:.|||..: :....|.|.....:||.:...|.:||:
Zfish   154 QRQVRHPFVHDLQDCWQTQRHIYIMCDYCSTGDLYTYWVMIGQFGEDVVKVFAAELGSALGFLHD 218

  Fly  1293 NKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDW 1357
            ..||:||:|::|:||..:|::::|||||.:. :..|.|..|.|||.:::|||||:...|..|.||
Zfish   219 CAIIHRDVKMENVLLTDQGHLRLADFGLSRR-LERGGRAFTICGTIQYMAPEVLSGGPYNHASDW 282

  Fly  1358 WGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVR-----YPRFLSLEAIAVMRRLLRKNPERRL 1417
            |.||:|:|.:..|:.|.|.:.:.    .::...||     .|:..|.....::..||.|.|.|||
Zfish   283 WSLGILLFALATGKFPVPPEPDH----CLMLRRVRSFPYDMPKTFSPSFALLLTELLCKTPARRL 343

  Fly  1418 GSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINH-------------LEDVSNFDEEFTS 1469
            .:.||    .|:|.||....:|..||:|.....:..:.:             ||...|||.:|.
Zfish   344 RTLER----FKRQTFFHGTPFDSHLLQKTPMELILELKNRPDRPAKARRGLTLESFPNFDCDFL- 403

  Fly  1470 EKAQLTPPKEP 1480
                |:.|..|
Zfish   404 ----LSSPCTP 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkn	NP_001097237.1	HR1_PKN_1	131..194	CDD:212012
		HR1_PKN_2	243..309	CDD:212013
		HR1_PKN_3	340..414	CDD:212015
		C2	530..611	CDD:301316
		STKc_PKN	1174..1499	CDD:270741	101/326 (31%)
		S_TKc	1174..1433	CDD:214567	86/264 (33%)
rskrb	XP_003200943.1	S_TKc	102..355	CDD:214567	86/264 (33%)
rskrb	XP_003200943.1	STKc_AGC	108..355	CDD:270693	84/258 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0694
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900