| Sequence 1: | NP_001361188.1 | Gene: | IL12RB2 / 3595 | HGNCID: | 5972 | Length: | 862 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001246162.1 | Gene: | Dscam1 / 35652 | FlyBaseID: | FBgn0033159 | Length: | 2038 | Species: | Drosophila melanogaster |
| Alignment Length: | 1019 | Identity: | 198/1019 - (19%) |
|---|---|---|---|
| Similarity: | 339/1019 - (33%) | Gaps: | 318/1019 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Human 2 AHTFRGCSLA--------FMFIIT------WLL--------------IKAKIDACKRGDVTVKPS 38
Human 39 HVILLGST------VNITCSLKPRQGCFHYSRRNKLILYKFDRRINFHHGHSLNSQVTGLPLGTT 97
Human 98 LFVCKLACINSDEIQICGAEIFVGVAPE-------------QPQNLSCIQKGEQGTVACTWERG- 148
Human 149 -----RDTHLYT--EYTLQLSGPKNLTWQKQCKDIYCDYLDFGINLTPESPESNFTAKVTAVNSL 206
Human 207 GSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRD--EGLVLLNRL-----RYRPSNS 264
Human 265 RLWNMV---NVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLD 326
Human 327 VWYMKRHI---DYSRQQISLFWKNLSVSEARGKILHYQV--------------TLQELT-GGKAM 373
Human 374 T---QNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEG-- 433
Human 434 -------------MDNILVTW-QPPRKDPSAV-QEYVV------EWRELHPGGDTQVPLNWLRSR 477
Human 478 PYNVSA---LISENIKSYICYEIRVYALSGDQGGCSS--ILGNSKHKAPLSGPHINAITEEKGSI 537
Human 538 LISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALT 602
Human 603 AAGESSHGNE---------------------REFCLQGKANWMAFVAPSICIAIIMVGIFSTHYF 646
Human 647 QQKVF----VLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDP----- 702
Human 703 ----EPLVI--------SEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRA 755
Human 756 LQAESRQLV-----------DLYKVLESRGSDPKPENPACP-WTVLPAGDLPTH-----DGYLPS 803
Human 804 NIDDLPSHEAPLADSLEELEPQHISLSVFPSSS-----LHPLTF 842 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| IL12RB2 | NP_001361188.1 | Lep_receptor_Ig | 28..110 | CDD:368845 | 12/87 (14%) |
| FN3 | 224..316 | CDD:238020 | 22/101 (22%) | ||
| WSXWS motif | 305..309 | 1/3 (33%) | |||
| FN3 | 423..511 | CDD:238020 | 22/113 (19%) | ||
| FN3 | 521..615 | CDD:238020 | 22/114 (19%) | ||
| Box 1 motif | 662..670 | 1/7 (14%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 725..755 | 5/29 (17%) | |||
| Required for STAT4 binding | 796..801 | 3/9 (33%) | |||
| Dscam1 | NP_001246162.1 | Ig | 38..130 | CDD:299845 | |
| IG | 57..133 | CDD:214652 | |||
| IG_like | 267..343 | CDD:214653 | |||
| Ig | 269..340 | CDD:143165 | |||
| IG_like | 353..425 | CDD:214653 | |||
| IGc2 | 361..413 | CDD:197706 | |||
| I-set | 433..527 | CDD:254352 | |||
| IGc2 | 446..517 | CDD:197706 | |||
| I-set | 533..618 | CDD:254352 | |||
| IGc2 | 544..607 | CDD:197706 | |||
| Ig | 641..714 | CDD:143165 | 5/19 (26%) | ||
| IGc2 | 735..804 | CDD:197706 | 13/83 (16%) | ||
| I-set | 819..914 | CDD:254352 | 23/118 (19%) | ||
| Ig | 833..921 | CDD:299845 | 24/111 (22%) | ||
| FN3 | 918..1011 | CDD:238020 | 22/99 (22%) | ||
| FN3 | 1018..1116 | CDD:238020 | 25/127 (20%) | ||
| FN3 | 1124..1217 | CDD:238020 | 22/105 (21%) | ||
| FN3 | 1222..1312 | CDD:238020 | 22/93 (24%) | ||
| Ig | 1339..1406 | CDD:299845 | 13/77 (17%) | ||
| FN3 | 1409..1499 | CDD:238020 | 17/103 (17%) | ||
| FN3 | 1504..1584 | CDD:238020 | 17/75 (23%) | ||
| Dscam_C | 1890..2008 | CDD:289151 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||