DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hig and Apoh

DIOPT Version :9

Sequence 1:	NP_724773.1	Gene:	hig / 35949	FlyBaseID:	FBgn0010114	Length:	958	Species:	Drosophila melanogaster
Sequence 2:	NP_001009626.1	Gene:	Apoh / 287774	RGDID:	1310625	Length:	345	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	74/263 - (28%)
Similarity:	112/263 - (42%)	Gaps:	31/263 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   707 VVVATSTCPQLTE-PLA---PLKLRLEGNKLGQRAHYECPEGFRLDGAWNA-TCLASGNWSSPTP 766
            |.:|..|||:..| |.|   |||...:.   |::..|.|..|:...|.... ||..:|.|...|.
  Rat    16 VAIAGRTCPKPDELPFAVVVPLKTFYDP---GEQIVYSCKPGYVSRGGMRRFTCPLTGMWPINTL 77

  Fly   767 TCHAIQCPRLELDDPHLSLIELNTSAWGRAV-FKCQWGFKLTGPAQLDCEPSGVWSGPVPRCKVI 830
            .|....||...:.:.  .::...|..:...: |.|..|:.|.|.:...|...|.||..:|.|..|
  Rat    78 KCIPRVCPFAGILEN--GVVRYTTFEYPNTIGFACNPGYYLNGTSSSKCTEEGKWSPELPVCARI 140

  Fly   831 QCVMPVAPLNGRIGGTSLSQRRLTVG------ALVTFSCNDGHSLVGESSIICTENGQWSHSPPF 889
            .|..|..|     ...:|.:.:.:||      ..|.|.|....::.|..::.||.:|.|:..|..
  Rat   141 TCPPPPIP-----KFAALKEYKTSVGNSSFYQDTVVFKCLPHFAMFGNDTVTCTAHGNWTQLPEC 200

  Fly   890 CKSQCPYPGDPPNGLIAPLKFNYDAGDYLSVQCRP--GFVQSYE-GPPERPKCQPDGRWSGPMPK 951
            .:.:||:|..|.||.:     ||.|...||.:.:.  |..::|: ..||..:|...|.||. :|.
  Rat   201 REVKCPFPSRPDNGFV-----NYPAKPVLSYKDKAVFGCHETYKLDGPEEVECTKTGNWSA-LPS 259

  Fly   952 CKS 954
            ||:
  Rat   260 CKA 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hig	NP_724773.1	PHA02927	705..952	CDD:222943	72/259 (28%)
		CCP	714..768	CDD:153056	18/58 (31%)
		CCP	<795..828	CDD:153056	10/33 (30%)
		CCP	832..891	CDD:153056	15/64 (23%)
		Sushi	894..952	CDD:278512	20/60 (33%)
Apoh	NP_001009626.1	PHA02927	41..260	CDD:222943	61/234 (26%)
Apoh	NP_001009626.1	Sushi_2	261..345	CDD:401094	1/2 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19325
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100