Protein Alignment hig and Selp

DIOPT Version :9

• Sequence 1: NP_724773.1
• Gene: hig / 35949
• FlyBaseID: FBgn0010114
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_037246.2
• Gene: Selp / 25651
• RGDID: 3656
• Length: 768
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 142/608 - (23%)
• Similarity: 199/608 - (32%)
• Gaps: 224/608 - (36%)

  Fly   480 CVKGKWVGPLCATNEEDDNGNVKFQPLYKSCHVNRIPSHLLLSYRNISVTPIPPNRGWRKTRLSK 544
            |..| :.||.|...:|              |....||.|:|:
  Rat   185 CYPG-FYGPECEYVQE--------------CGKFDIPQHVLM----------------------- 211

  Fly   545 STLLSNTEINVGWDLPHGHSLQARCQELGIYKLLGESRVLC-SNGLWAPRMPSCVPTTVLTNYSE 608
                 |....:| |..........|.| | |.|.|.|.:.| ::|:|....|.|......:
  Rat   212 -----NCSHPLG-DFSFSSQCTFSCPE-G-YDLNGPSEMQCLASGIWTNNPPQCKAVQCQS---- 264

  Fly   609 DSAPSIRIKIFNGSHSFEPSGVMAVPPHSTVLMDCMYP------------------RVRGTPEWS 655
                                  :..|.|.|  |||.:|                  |:||:....
  Rat   265 ----------------------LEAPLHGT--MDCTHPLAAFAYDSSCKFECQPGYRMRGSDILH 305

  Fly   656 WTSWYMQYSTGWS---PAQEEKAVRYRLSIKNIEN-----------------NDSGTFTCTSPRG 700
            .|.     |..||   |..|      .::.:.:|:                 |.|.||.||....
  Rat   306 CTD-----SGQWSEPLPTCE------AIACEPLESPLHGSMDCFPSTGAFGYNSSCTFRCTEGFV 359

  Fly   701 LTNSIAVVVA-----TSTCP-----QLTEPLAPLKLRLEGN------KLGQRAHYECPEGFRLDG 749
            |..:.|:..|     |:..|     |..|...|.|.::..:      |......:.|.||..|.|
  Rat   360 LMGNDAIHCADLGQWTAPAPVCEALQCQEFPVPSKAQVSCSDPFGTLKYQSACSFSCDEGSLLVG 424

  Fly   750 AWNATCLASGNWSSPTPTCHAIQC-PRLELDDPHLSLIE-LNTSAW-GRAVFKCQWGFKLTGPAQ 811
            |....|||:|:||...|.|.|:.| |.|..::..::.|: |..|.: ....|.|..||.|:||.:
  Rat   425 ASVIRCLATGHWSEAPPECQAVSCTPLLSPENGTMTCIQPLGHSNYKSTCQFMCDEGFYLSGPER 489

  Fly   812 LDCEPSGVWSGPVPRCKVIQCVMPVAPLNGRIGGTSLSQRRLTVGALVTFSCNDGHSLVGESSII 876
            |||.|||.|:|..|.|:.|:|....||..|.: ..|......:||:...||||:...|:|..::.
  Rat   490 LDCSPSGHWTGSPPMCEAIKCPEIFAPEQGSL-DCSHVHGEFSVGSTCHFSCNEEFELLGSRNVE 553

  Fly   877 CTENGQWSHSPPFCKS---------QCPYPGDPPNG----------------------------- 903
            ||.:|:||..||.||.         :||....|..|
  Rat   554 CTVSGRWSAPPPTCKGVTSLPVPSVRCPALTTPGQGTMSCRHHLESFGPNTTCYFGCKTGFTLRG 618

  Fly   904 -------------LIAPL------------------------KFNYDAGDYLSVQCRPGFVQSYE 931
                         .:.|:                        .|:|  |...:..|..|  ||..
  Rat   619 ANSLRCGASGQWTAVTPVCRAVKCSELHMDTAVAMNCSNPWGNFSY--GSTCAFHCPEG--QSLN 679

  Fly   932 GPPERPKCQPDGRWSGPMPKCKS 954
            | ..|..|:.||.||..||.|::
  Rat   680 G-SARTTCREDGHWSDAMPTCQA 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hig	NP_724773.1	PHA02927	705..952	CDD:222943	91/340 (27%)
		CCP	714..768	CDD:153056	19/64 (30%)
		CCP	<795..828	CDD:153056	16/32 (50%)
		CCP	832..891	CDD:153056	20/58 (34%)
		Sushi	894..952	CDD:278512	21/123 (17%)
Selp	NP_037246.2	CLECT_selectins_like	42..160	CDD:153062
		EGF_CA	<168..195	CDD:238011	4/10 (40%)
		CCP	200..258	CDD:153056	19/88 (22%)
		PHA02927	276..505	CDD:222943	64/239 (27%)
		PHA02927	443..699	CDD:222943	69/261 (26%)
		Endocytosis signal. /evidence=ECO:0000305	756..759
		Interaction with SNX17. /evidence=ECO:0000250	759..768

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I11952
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19325
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5897
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.100