Protein Alignment hig and selp

DIOPT Version :10

• Sequence 1: NP_724773.1
• Gene: hig / 35949
• FlyBaseID: FBgn0010114
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: XP_031756924.1
• Gene: selp / 100485005
• XenbaseID: XB-GENE-482807
• Length: 976
• Species: Xenopus tropicalis
• Alignment Length: 556
• Identity: 139/556 - (25%)
• Similarity: 208/556 - (37%)
• Gaps: 119/556 - (21%)

  Fly   478 IRCVKGKWVG--PLCATNE--------------EDDNGNVKFQPLYKS-CHVNRIPSHLLLSYRN 525
            |:| |.:|.|  |.||..:              :|:.|  |||  |.| |..:......|....:
 Frog   220 IQC-KEEWSGLVPQCAVVDCPRLVVPELGSMECKDEYG--KFQ--YNSNCSFSCNEGFTLTGPNS 279

  Fly   526 ISVT------------------PIP-PNRGWRKTRLSKSTLLSNT----EINVGWDLPHGHSLQA 567
            :..|                  .|| |..|..|..........|:    ..|.|:.|...:|||.
 Frog   280 LQCTSSGSWSSDVPACKAVVCPSIPVPEHGSMKCEDDYEEFQYNSNCSFSCNEGFTLAGSNSLQC 344

  Fly   568 RCQELGIYKLLGESRVLCSNGLWAPRMPS-----CVPTTVLTNYS---EDSAPSIRIK------- 617
                             .|:|.|:..:|:     |.|.|...:.|   ||.....:..
 Frog   345 -----------------TSSGSWSSNVPTCEAVVCPPITCPEHGSKECEDDFGEFQYNSNCSFSC 392

  Fly   618 ----IFNGSHSFE--PSGVMAVPPHSTVLMDC---MYPRVRGTPEWSWTSWYMQYSTGWSPAQEE 673
                |..||:|.:  .||..:....:...:||   :.|.: |:.|........:|::..|.:.:|
 Frog   393 SEGFILTGSNSLQCTSSGSWSSDVPACKAVDCPHLVVPEL-GSMECKDEHGEFKYNSNCSFSCKE 456

  Fly   674 KAVRYRLSIKNIENNDSGTFTCTSPRGLTNSIAVVVATSTCPQLTEP-LAPLKLR--LEGNKLGQ 735
                      .....:|.:..|||....::.:....|. .||.:..| ...:|..  .|..:...
 Frog   457 ----------GFTLTESNSLQCTSSGSWSSDVPACKAV-VCPSIPVPEHGSMKCEDDYEEFQYNS 510

  Fly   736 RAHYECPEGFRLDGAWNATCLASGNWSSPTPTCHAIQCPRLELDDPHLSLIELNTSAW---GRAV 797
            :..:.|.|||.|.|:.:..|.:||:|||..|||.|:.||.:.|.:......|.:...:   ....
 Frog   511 KCSFSCNEGFILAGSNSLQCTSSGSWSSDVPTCKAVVCPSIPLPEHGSKECENDYGEFQYNSNCS 575

  Fly   798 FKCQWGFKLTGPAQLDCEPSGVWSGPVPRCKVIQCVMPVAPLNGRIGGTSLSQR--RLTVGALVT 860
            |.|..||.||||..|.|..||.||..||.||.:.|...|.|   .:|.......  |....:..:
 Frog   576 FSCSEGFTLTGPNSLQCTSSGSWSSDVPACKAVDCPHLVVP---ELGSMECKDEYGRFQYNSNCS 637

  Fly   861 FSCNDGHSLVGESSIICTENGQWSHSPPFCKS-QCPYPGDPPNGLIAPL----KFNYDAGDYLSV 920
            |||.:|.:|.|.:|:.|..:|.|....|.|:: .||....|.:|.|...    ||.|::.  .||
 Frog   638 FSCKEGFTLTGSNSLQCISSGSWGSDVPTCEAVACPDIPVPEHGFIKCEDDYGKFQYNSN--CSV 700

  Fly   921 QCRPGFVQSYEGPPERPKCQPDGRWSGPMPKCKSYE 956
            .|..||   :....:..||...|.||..:|.|::.:
 Frog   701 SCNEGF---FLTGSDSLKCTSSGSWSSDVPACEAVQ 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hig	NP_724773.1	Ig_3	612..696	CDD:464046	15/99 (15%)
		PHA02927	705..952	CDD:222943	80/259 (31%)
selp	XP_031756924.1	CLECT_selectins_like	20..138	CDD:153062
		EGF_CA	142..173	CDD:238011
		PHA02927	178..419	CDD:222943	46/220 (21%)
		PHA02927	439..667	CDD:222943	67/241 (28%)
		CCP	672..730	CDD:153056	19/62 (31%)
		PHA02927	<710..909	CDD:222943	7/24 (29%)