DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4p3 and CYP721A1

DIOPT Version :9

Sequence 1:	NP_610473.1	Gene:	Cyp4p3 / 35948	FlyBaseID:	FBgn0033397	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_177649.1	Gene:	CYP721A1 / 843850	AraportID:	AT1G75130	Length:	505	Species:	Arabidopsis thaliana

Alignment Length:	571	Identity:	133/571 - (23%)
Similarity:	235/571 - (41%)	Gaps:	135/571 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLILWLVGAFIVLIQWI-----------------YRL----NRDYCILGFFAKRIRTKNGQNPES 44
            ::..:||..||....|:                 ||:    :.:...|...||.....:|:||..
plant     9 LVFFFLVFRFIYSNIWVPWRIQSHFKKQSVTGPSYRIFSGNSGEVSRLTAEAKSKPIPSGRNPHE 73

  Fly    45 ----IAPLVKGSTIFANSFDLYGKDHSGVFEHSRDCAKKLGKSYAEYAMGTAIYNVIDADSAERV 105
                :||                        |..:.::..||::. |..|:   ..:.|.|
plant    74 FVHRVAP------------------------HYHEWSRVYGKTFL-YWFGS---KPVVATS---- 106

  Fly   106 LNDPNLINK----GTIYDFL--HPFLR----TGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIF 160
              ||.||.:    |..:|.:  :|..:    .||....|.:|...|::....|....|.::....
plant   107 --DPRLIREALTTGGSFDRIGHNPLSKLLYAQGLPGLRGDQWAFHRRIAKQAFTMEKLKRWVPQM 169

  Fly   161 ITESLKFLEQFK----GNDEAIISLNEVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFRQIEE 221
            :|.::..:|:::    |.:|..:.:::.:...:...:..||.|..::|  .||      ..:::|
plant   170 VTSTMMLMEKWEDMRNGGEEIELEVHKEMHNLSAEMLSRTAFGNSVEE--GKG------IFELQE 226

  Fly   222 CFIRRMSNPLLWSDTL--FKMFAEKDYASALDVVHGFSSEI--IAKR-RDQLNDEIDSRGNTQTA 281
            ..: |:...:.||..:  |:.|..|.           :.||  |.|: |..:...|:   |.:||
plant   227 RMM-RLFYLVRWSVYIPGFRFFPSKT-----------NREIWRIEKQIRVSILKLIE---NNKTA 276

  Fly   282 EDELFTSKKRFAMLDTLILAEKDGLIDHIGICEEVD---TLMFEGYDTTSIGLMFGLMNMSLYPE 343
            .::..|..:.|....|    .::|..:.:||.|..|   |..|...:||:..:.|.|:.:::..|
plant   277 VEKSGTLLQAFMSPYT----NQNGQEEKLGIEEVTDECKTFYFAAKETTANLMTFVLVLLAMNQE 337

  Fly   344 EQEKCYQEIQANIDDELNILNIGQ--------LNKLKNLEYFIKETMRLFPSVPAMGRETTRETE 400
            .|         ||..|..|..:||        |..||.|...|.||:||:|....:.|:|.:..:
plant   338 WQ---------NIAREEVICVLGQTGLPTLDILQDLKTLSMIINETLRLYPPAMTLNRDTLKRAK 393

  Fly   401 LSNGLILPKGSQIFVHVFDIHRNPEYW-DSPEEFRPERFLPENSQNRHTYAYIPFSAGQRNCIGQ 464
            |.: |.:|.|:|:::.|..:|.:.|.| |..|||.|.||   ....:.:...:||..|.|.|:||
plant   394 LGD-LDIPAGTQLYLSVVAMHHDKETWGDDAEEFNPRRF---EDPKKQSALLVPFGLGPRTCVGQ 454

  Fly   465 KFAMQEMKTLMVALLK--QFQILPEIDPKTIVFQTGLTLRTKNQIHVKLVR 513
            ..|:.|.||::..:||  .|::.|......::|   :||:.:|..|:...|
plant   455 NLAVNEAKTVLATILKYYSFRLSPSYAHAPVLF---VTLQPQNGAHLLFTR 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	115/483 (24%)
CYP721A1	NP_177649.1	p450	26..495	CDD:386267	125/545 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050