DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p3 and CYP86C4

DIOPT Version :9

Sequence 1:	NP_610473.1	Gene:	Cyp4p3 / 35948	FlyBaseID:	FBgn0033397	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_172774.1	Gene:	CYP86C4 / 837873	AraportID:	AT1G13150	Length:	529	Species:	Arabidopsis thaliana

Alignment Length:	538	Identity:	128/538 - (23%)
Similarity:	222/538 - (41%)	Gaps:	120/538 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LILWLVGAFIVLIQWIYRLNRDYCILGFFAKRIRTKNGQNPESIAPL---VKGSTI--FANSFDL 61
            |:|.|:|.|:            :|.|   .:::..|.|       |:   |.|.|:  |.:..|:
plant    16 LLLSLLGLFV------------FCCL---REKLTNKRG-------PMLWPVFGITLEFFFHINDV 58

  Fly    62 YGKDHSGVFEHSRDCAKKLGKSYAEYAMGTAIYNVIDAD-----------SAERVLNDPNLIN-- 113
            ||    .|....:.|            .||.:|..:..|           :.|.:|. .|..|
plant    59 YG----WVTRSLKKC------------RGTFLYRGVWLDGSYGAVTCVPANVEYMLK-TNFKNFP 106

  Fly   114 KGTIY-DFLHPFLRTGLLTSTGKKWHARRKMLSPTFHFN--ILNQF---QEIFITESLKFLEQFK 172
            |||.: ...:..|..|:..:....|..:|:::....|..  :.:.|   |.:...:.||.:|.|.
plant   107 KGTFFKSRFNDLLEEGIFNADDDSWKEQRRIIITEMHSTGFVEHSFQTTQHLVRKKLLKVMESFA 171

  Fly   173 GNDEAIISLNEVIPRFTLNSICETAMGVKLDEMAEKGDR--YRENFRQ-IEECFIRRMSNPLLWS 234
            .:.|| ..|.:|..|.|.:.||...:|...:.:|....:  :.:.|.: .|....|.|..|.:|.
plant   172 KSQEA-FDLQDVFLRLTFDIICLAGLGADPETLAVDLPQVPFAKAFEEATESTLFRFMIPPFIWK 235

  Fly   235 -----DTLFKMFAEKDYASALDVVHGFSSEIIAKRRDQLNDE--IDSRGN---------TQTAED 283
                 ||.:    ||....|:.|||||..::|..|..:|.:|  :|:|.:         :...|:
plant   236 PMRFLDTGY----EKGLRIAVGVVHGFVDKMIVDRICELKEEETLDNRSDVLSRIIQIESHKREN 296

  Fly   284 ELFTSKKRF--AMLDTLILAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQE 346
            |:..|..||  ....:.|||                     |.||:|:.|.:....:..:||.:.
plant   297 EIDPSTIRFFRQFCTSFILA---------------------GRDTSSVALSWFCWVIQKHPEVEN 340

  Fly   347 KCYQEIQ--------ANIDDELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETELSN 403
            |...||:        :......::..:.:||.:..|:..:.||:||||.:|...::...:..|.:
plant   341 KIICEIREILRQRGDSPTSKNESLFTVKELNNMVYLQAALSETLRLFPPIPMEMKQAIEDDVLPD 405

  Fly   404 GLILPKGSQIFVHVFDIHRNPEYWDSP-EEFRPERFLPENS-QNRHTYAYIPFSAGQRNCIGQKF 466
            |..:.|||:::..::.:.|....|... |.|||||::.... .:...:.|:.|:||.|.|||:.|
plant   406 GTFVRKGSRVYFSIYAMGRMESIWGKDCEIFRPERWIQAGKFVSDDQFKYVVFNAGPRLCIGKTF 470

  Fly   467 AMQEMKTLMVALLKQFQI 484
            |..:||.:..::|.::.|
plant   471 AYLQMKMIAASVLLRYSI 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	115/483 (24%)
CYP86C4	NP_172774.1	CYP86A	73..510	CDD:410687	107/443 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010