DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p3 and CYP735A1

DIOPT Version :9

Sequence 1:	NP_610473.1	Gene:	Cyp4p3 / 35948	FlyBaseID:	FBgn0033397	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_198661.1	Gene:	CYP735A1 / 833833	AraportID:	AT5G38450	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	137/567 - (24%)
Similarity:	229/567 - (40%)	Gaps:	123/567 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLILWLVGAFIVLIQWIYRLNRD----YCILGFFAKRIRTKNGQNPESIAPL----VKGSTIFAN 57
            ||:..|....::.:..|.|:..|    |.:.....|:|..:.|.......||    ::.|.:.:.
plant     1 MLLTILKSLLVIFVTTILRVLYDTISCYWLTPRRIKKIMEQQGVTGPKPRPLTGNILEISAMVSQ 65

  Fly    58 S---------FDLYGKDHSGVFEHSRDCAKKLGKSYAEYAMGTAIYN-------VIDADSAERVL 106
            |         .|:.|:    :..|....:|:.||.:       .::|       :.:.:..:.:|
plant    66 SASKDCDSIHHDIVGR----LLPHYVAWSKQYGKRF-------IVWNGTDPRLCLTETELIKELL 119

  Fly   107 NDPN-------LINKGTIYDFLHPFLRTGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIFITES 164
            ...|       |..:||     ..|:..|||.:.|:.||.:|.:.:|.|....|..:....:..:
plant   120 MKHNGVSGRSWLQQQGT-----KNFIGRGLLMANGQDWHHQRHLAAPAFTGERLKGYARHMVECT 179

  Fly   165 LKFLEQFK---GNDEAIISLNEVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFRQIEE----- 221
            .|.:|:.:   |.....:.:.|.:.:.|.:.|..|..|...    |||.....:...::.
plant   180 SKLVERLRKEVGEGANEVEIGEEMHKLTADIISRTKFGSSF----EKGKELFNHLTVLQRRCAQA 240

  Fly   222 ----CFIRRMSNPLLWSDTLFKMFAEKDYASALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQTAE 282
                ||......|..::         ::..|....|.....|||..|||     ....|.:.|..
plant   241 TRHLCFPGSRFLPSKYN---------REIKSLKKEVERLLIEIIQSRRD-----CAEMGRSSTHG 291

  Fly   283 DELFTSKKRFAMLDTLILAEKDGLIDHIG---------ICEEVDTLMFEGYDTTSIGLMFGLMNM 338
            |:|.          .|:|.|.|  ||...         |.:|..|..|.|::||::.|.:..|.:
plant   292 DDLL----------GLLLNEMD--IDKNNNNNNNNLQLIMDECKTFFFAGHETTALLLTWTTMLL 344

  Fly   339 SLYPEEQEKCYQEIQANIDDELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETELSN 403
            :..|..|||..:|:: .:.....:.::.||:||.:|...|.|::||:|....:.|....:.:|.:
plant   345 ADNPTWQEKVREEVR-EVFGRNGLPSVDQLSKLTSLSKVINESLRLYPPATLLPRMAFEDLKLGD 408

  Fly   404 GLILPKGSQIFVHVFDIHRNPEYW-DSPEEFRPERF--LPENSQNRHTYAYIPFSAGQRNCIGQK 465
             |.:|||..|::.|..||.:.|.| ....:|.||||  .|..| .||   :|||:||.||||||:
plant   409 -LTIPKGLSIWIPVLAIHHSEELWGKDANQFNPERFGGRPFAS-GRH---FIPFAAGPRNCIGQQ 468

  Fly   466 FAMQEMKTLMVALLKQFQILPEIDPKTIVFQTGLTLRTKNQIHVKLV 512
            ||:.|.|.::..|:.:|..       ||         :||..|..:|
plant   469 FALMEAKIILATLISKFNF-------TI---------SKNYRHAPIV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	120/497 (24%)
CYP735A1	NP_198661.1	PLN02290	1..518	CDD:215164	137/567 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.050