DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p3 and CYP714A1

DIOPT Version :9

Sequence 1:	NP_610473.1	Gene:	Cyp4p3 / 35948	FlyBaseID:	FBgn0033397	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_568463.1	Gene:	CYP714A1 / 832560	AraportID:	AT5G24910	Length:	532	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	127/562 - (22%)
Similarity:	236/562 - (41%)	Gaps:	99/562 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ILWLV--GAF---------IVLIQWIYRLNRDYCILGFFAKRIRTKNGQNPE---------SIAP 47
            |.|:|  |..         ::..||  |:.|...:.|..........|..||         |.:.
plant    12 ISWIVVIGVLGLGIRVYGKVMAEQW--RMRRKLTMQGVKGPPPSLFRGNVPEMQKIQSQIMSNSK 74

  Fly    48 LVKGSTIFANSFDLYGKDHSGVFEHSRDCAKKLGKSYAEYAMGTAIYNVIDADSAERVLNDPNLI 112
            ...|..|.|:.:.      |.:|.:.....|:.|:.|. |:.|...:..::.....:.||..|.:
plant    75 HYSGDNIIAHDYT------SSLFPYLDHWRKQYGRVYT-YSTGVKQHLYMNHPELVKELNQANTL 132

  Fly   113 NKGT---IYDFLHPFLRTGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIFITESL----KFLEQ 170
            |.|.   :...|...|..|::||.|..|..:|::::|.|..:.:.....:.:..::    |:.|.
plant   133 NLGKVSYVTKRLKSILGRGVITSNGPHWAHQRRIIAPEFFLDKVKGMVGLVVESAMPMLSKWEEM 197

  Fly   171 FKGNDEAI--ISLNEVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFRQIEECF--IRRMSNPL 231
            .|...|.:  |.::|.:...:.:.|.....|              .:|.:.:|.|  :|.:...:
plant   198 MKREGEMVCDIIVDEDLRAASADVISRACFG--------------SSFSKGKEIFSKLRCLQKAI 248

  Fly   232 LWSDTLFKMFAEKDYASALDVVHGFSSEIIAKRR------DQLNDEIDSR--GNTQTAEDELFTS 288
            ..::.||.:             :||:..:...::      |:|...|:|.  ...:..|.|....
plant   249 THNNILFSL-------------NGFTDVVFGTKKHGNGKIDELERHIESLIWETVKERERECVGD 300

  Fly   289 KKRFAMLDTLIL----AEKDGLID------HIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPE 343
            .|:..|  .|||    :..||.::      ...:.:...::.|.|::|:::.:.:.||.::|.|.
plant   301 HKKDLM--QLILEGARSSCDGNLEDKTQSYKSFVVDNCKSIYFAGHETSAVAVSWCLMLLALNPS 363

  Fly   344 EQEKCYQEIQANIDDELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETELSNGLILP 408
            .|.:...|:..:..:  .|.:...::.||.:...|:||:||:|....:.||...:|:|.| |::|
plant   364 WQTRIRDEVFLHCKN--GIPDADSISNLKTVTMVIQETLRLYPPAAFVSREALEDTKLGN-LVVP 425

  Fly   409 KGSQIFVHVFDIHRNPEYWDS-PEEFRPERFLPENSQN-RHTYAYIPFSAGQRNCIGQKFAMQEM 471
            ||..|:..:..:||:||.|.: ..||.||||....|:. :|..:::||..|.|.|:|:.|.|.|:
plant   426 KGVCIWTLIPTLHRDPEIWGADANEFNPERFSEGVSKACKHPQSFVPFGLGTRLCLGKNFGMMEL 490

  Fly   472 KTLMVALLKQFQI-LPEIDPKTIVF------QTGLTLRTKNQ 506
            |.|:..::.:|.. |......:.||      |.|:.:|...|
plant   491 KVLVSLIVSRFSFTLSPTYQHSPVFRMLVEPQHGVVIRVLRQ 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	112/488 (23%)
CYP714A1	NP_568463.1	p450	37..530	CDD:299894	120/531 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960