DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4p3 and CPD

DIOPT Version :9

Sequence 1:	NP_610473.1	Gene:	Cyp4p3 / 35948	FlyBaseID:	FBgn0033397	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_196188.1	Gene:	CPD / 830453	AraportID:	AT5G05690	Length:	472	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	124/537 - (23%)
Similarity:	209/537 - (38%)	Gaps:	104/537 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AFIVLIQWIYRLNRDYCILGFFAKRIRT---KNGQNPESIAPLVKGSTIFANSFDL---YGKDHS 67
            ||::|:..|        ..||.....||   :.|..|.|:     |..:...:|.|   |..::.
plant     5 AFLLLLSSI--------AAGFLLLLRRTRYRRMGLPPGSL-----GLPLIGETFQLIGAYKTENP 56

  Fly    68 GVFEHSRDCAKKLGKSYAEYAMGTAIYNVIDADSAERVLNDPNLINKGTIYDFLHPFLRTGLLTS 132
            ..|...|  ..:.|..:..:..|.......|.::...||.     |:|.:::..:|.....||
plant    57 EPFIDER--VARYGSVFMTHLFGEPTIFSADPETNRFVLQ-----NEGKLFECSYPASICNLL-- 112

  Fly   133 TGK------KWHARRKMLSPTFHF---NILNQFQEIFITESLKF-LEQFKGNDEAIISLNEVIPR 187
             ||      |....::|.|.|..|   :|:.....:.|...::| |:.:...    :.|.|...:
plant   113 -GKHSLLLMKGSLHKRMHSLTMSFANSSIIKDHLMLDIDRLVRFNLDSWSSR----VLLMEEAKK 172

  Fly   188 FTLNSICETAMGVKLDEMAEKGDRYRENFRQIEECFIRRMSNPL-LWSDTLFKMF-AEKDYASAL 250
            .|.....:..|.....|.:|.   .|:.:..:.|.|   .|.|| |:|.|..|.. |.:..|.||
plant   173 ITFELTVKQLMSFDPGEWSES---LRKEYLLVIEGF---FSLPLPLFSTTYRKAIQARRKVAEAL 231

  Fly   251 DVVHGFSSEIIAKRRDQLNDEIDSRGNTQTAEDELFTSKKRFAMLDTLILAEKDGLIDHIGICEE 315
            .||       :.|||::              |:|....||  .||..|:.|: ||..|.    |.
plant   232 TVV-------VMKRREE--------------EEEGAERKK--DMLAALLAAD-DGFSDE----EI 268

  Fly   316 VD---TLMFEGYDTTSIGLMFGLMNMSLYP-------EEQEKCYQEIQANIDDELNILNIGQLNK 370
            ||   .|:..||:|||..:...:..::..|       ||.||    |:|...|..::    :.:.
plant   269 VDFLVALLVAGYETTSTIMTLAVKFLTETPLALAQLKEEHEK----IRAMKSDSYSL----EWSD 325

  Fly   371 LKNLEY---FIKETMRLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSPEE 432
            .|::.:   .:.||:|:...:..:.|....:.|: .|..:|||.::|.....:|.:|.::.....
plant   326 YKSMPFTQCVVNETLRVANIIGGVFRRAMTDVEI-KGYKIPKGWKVFSSFRAVHLDPNHFKDART 389

  Fly   433 FRPERFLPENSQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTIVFQT 497
            |.|.|:...:.....:..:.||..|.|.|.|.:.|...:...:..|:..|..:|....|.:.|.
plant   390 FNPWRWQSNSVTTGPSNVFTPFGGGPRLCPGYELARVALSVFLHRLVTGFSWVPAEQDKLVFFP- 453

  Fly   498 GLTLRTKNQIHVKLVRR 514
              |.||:.:..:.:.||
plant   454 --TTRTQKRYPIFVKRR 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	110/478 (23%)
CPD	NP_196188.1	p450	1..472	CDD:386267	124/537 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010