DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p3 and CYP86C2

DIOPT Version :9

Sequence 1:	NP_610473.1	Gene:	Cyp4p3 / 35948	FlyBaseID:	FBgn0033397	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_189243.1	Gene:	CYP86C2 / 822212	AraportID:	AT3G26125	Length:	541	Species:	Arabidopsis thaliana

Alignment Length:	453	Identity:	106/453 - (23%)
Similarity:	192/453 - (42%)	Gaps:	86/453 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 KGTIY-DFLHPFLRTGLLTSTGKKWHARRKMLSPTFHFN--ILNQFQ---EIFITESLKFLEQFK 172
            ||..| :.....|..|:..:..:.|..:|:::....|..  :.:.||   ::...:.||.:|.|.
plant   114 KGEFYKERFRDLLEDGIFNADDESWKEQRRIIITEMHSTRFVDHSFQTTRDLIERKLLKVMESFS 178

  Fly   173 GNDEAIISLNEVIPRFTLNSICETAMGVKLDEMAEKGD-----RYRENFRQ-IEECFIRRMSNPL 231
            .:.|| ..|.|::.|.|.::||...:|   |:.....|     .:.:.|.: .|....|.|..|.
plant   179 KSQEA-FDLQEILLRLTFDNICIAGLG---DDPGTLDDDLPHVPFAKAFEEATESTLFRFMIPPF 239

  Fly   232 LWSD-TLFKMFAEKDYASALDVVHGFSSEIIAKRRDQLNDE--------------IDSRGNTQTA 281
            :|.. ..|.:..||....|::.||.|..:::.:|...|.|:              |....:.:..
plant   240 VWKPMKFFDIGYEKGLREAVETVHNFIDKMVVERIAMLKDQGTLANSKSDVLSRLIQIESHKRGD 304

  Fly   282 EDELFTSKKRFAMLDTLILAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQE 346
            |::.||:|.......:.|||                     |.||:|:.|.:....::.:||.:.
plant   305 ENDRFTAKFFRQFCTSFILA---------------------GRDTSSVALTWFFWLITKHPEVET 348

  Fly   347 KCYQEIQANIDDELNILN----------------------IGQLNKLKNLEYFIKETMRLFPSVP 389
            |...||:       .|||                      :.:||.:..|:..:.|::||:|.:|
plant   349 KILHEIR-------EILNQREKNKYKLDETGEKESSRHFTVKELNDMVYLQAALSESLRLYPPIP 406

  Fly   390 AMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSP-EEFRPERFLPENSQ--NRHTYAY 451
            ...::.|.|....:|..|.|||:::..|:.:.|....|... |.|:|||:: :..|  :...:.|
plant   407 MEMKQATEEDVFPDGTFLRKGSRVYFSVYAMGRMESIWGKDCEMFKPERWI-QGGQYVSDDQFKY 470

  Fly   452 IPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTIVFQTGLTLRTKNQIHVKLVRR 514
            :.|:||.|.|:|:.||..:||.:..::|..:.|..:.| ..:|.:...||..|:.:.|::..|
plant   471 VVFNAGPRLCLGKTFAYLQMKMVAASILLNYSIKVDQD-HVVVPRVTTTLYMKHGLKVRITPR 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	103/442 (23%)
CYP86C2	NP_189243.1	PLN03195	42..533	CDD:215627	106/453 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910