DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p3 and CYP704A2

DIOPT Version :9

Sequence 1:	NP_610473.1	Gene:	Cyp4p3 / 35948	FlyBaseID:	FBgn0033397	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_182075.1	Gene:	CYP704A2 / 819159	AraportID:	AT2G45510	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	528	Identity:	132/528 - (25%)
Similarity:	230/528 - (43%)	Gaps:	58/528 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FIVLIQWIYRLNRDYCILGFFAKRIRTKNGQNPESIAPLVKGSTIFANSFD-LYGKDHSGVFEHS 73
            ||||           |...:...||.|...:|.:..||      :.|..|| |:..|.  ::::.
plant    16 FIVL-----------CFTIYLMIRIFTGKSRNDKRYAP------VHATVFDLLFHSDE--LYDYE 61

  Fly    74 RDCAKKLGKSYAEYAMGTAIYNVIDADSAERVLND--PNLINKGTIYDFLHPFLRTGLLTSTGKK 136
            .:.|:: ..:|...:.|.:.....|..:.|.:|..  .|.....:..:.:...|..|:....|:|
plant    62 TEIARE-KPTYRFLSPGQSEILTADPRNVEHILKTRFDNYSKGHSSRENMADLLGHGIFAVDGEK 125

  Fly   137 WHARRKMLSPTFHFNILNQFQ-EIFITESLK---FLEQFKGNDEAIISLNEVIPRFTLNSICETA 197
            |..:||:.|..|...:|..|. .:|...:.|   |:.:|..:.:| ....:::.|.||:||.:..
plant   126 WRQQRKLSSFEFSTRVLRDFSCSVFRRNASKLVGFVSEFALSGKA-FDAQDLLMRCTLDSIFKVG 189

  Fly   198 MGVK---LDEMAEKGDRYRENFRQIEECFIRRMSNPLLWSDTLFKMFAEKDYASALDVVHGFSSE 259
            .||:   ||..:::|..:.|.|.:.......|..:||......|.:.::.....::..:..|...
plant   190 FGVELKCLDGFSKEGQEFMEAFDEGNVATSSRFIDPLWKLKWFFNIGSQSKLKKSIATIDKFVYS 254

  Fly   260 IIAKRRDQLNDEIDSRGNTQTAEDELFTSKKRFAMLDTLILAEKD--GLIDHIGICEEVDTLMFE 322
            :|..:|.:|..|    .||...||.|    .||     |:.:|||  .:.|.. :.:.:...|..
plant   255 LITTKRKELAKE----QNTVVREDIL----SRF-----LVESEKDPENMNDKY-LRDIILNFMIA 305

  Fly   323 GYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQ---------ANIDDELNILNIGQLNKLKNLEYFI 378
            |.|||:..|.:.|..:...|..|||..|||:         .:::..:..:|...|:::..|...:
plant   306 GKDTTAALLSWFLYMLCKNPLVQEKIVQEIRDVTFSHEKTTDVNGFVESINEEALDEMHYLHAAL 370

  Fly   379 KETMRLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYW-DSPEEFRPERFLPEN 442
            .||:||:|.||...|....:..|.:|..:.||..|:...:.:.|....| ...|||:|||:|.:.
plant   371 SETLRLYPPVPVDMRCAENDDVLPDGHRVSKGDNIYYIAYAMGRMTYIWGQDAEEFKPERWLKDG 435

  Fly   443 -SQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTIVFQTGLTLRTKNQ 506
             .|....:.:|.|.||.|.|:|:.||.::||.:.:|||..|:.....:...:.::..|||.....
plant   436 LFQPESPFKFISFHAGPRICLGKDFAYRQMKIVSMALLHFFRFKMADENSKVYYKRMLTLHVDGG 500

  Fly   507 IHVKLVRR 514
            :|:..:.|
plant   501 LHLCAIPR 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	119/473 (25%)
CYP704A2	NP_182075.1	PLN03195	15..509	CDD:215627	132/528 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920