DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p3 and Cyp4f37

DIOPT Version :9

Sequence 1:	NP_610473.1	Gene:	Cyp4p3 / 35948	FlyBaseID:	FBgn0033397	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001093657.1	Gene:	Cyp4f37 / 677156	MGIID:	3780112	Length:	546	Species:	Mus musculus

Alignment Length:	467	Identity:	150/467 - (32%)
Similarity:	232/467 - (49%)	Gaps:	40/467 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 HSGVFEHSRD---CAKKLGKSYAEYA---MGTAI--YNVIDADSAERVLNDPNLI--NKGTIYDF 120
            |.|:.||:.:   ...:.|::|.:..   :|..|  ..::|......:|....|:  ...|.:.|
Mouse    63 HLGMIEHNEEGMQLMTEAGQTYRDVHLCWLGPVIPVLRIVDPAFVAPLLLASALVAPKDTTFHTF 127

  Fly   121 LHPFLRTGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIFITESLKFL----EQFKGNDEAIISL 181
            :.|:|..||..::|.||...|::|:|.|||:||..:.:|| .:|:..:    :.......|.:.:
Mouse   128 VKPWLGDGLFLNSGDKWSRHRRLLTPAFHFDILKPYVKIF-NQSVNIMHAKWKHLSSEGSARLEM 191

  Fly   182 NEVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFRQIEECFIRRMSNPLLWSDTLFKMFAE-KD 245
            .|.|...||:|:.:...|.. ....|....|.....::....|:|.....|:.|.|:...|: :.
Mouse   192 FEHISLMTLDSLQKCLFGFD-SNCQESPSEYISAILELSSLVIKRSHQLFLFVDFLYYHTADGRR 255

  Fly   246 YASALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQTAEDELFTSK---KRFAMLDTLILAEKD--- 304
            :..|.|:||.|:..:|.:||..|:.:         ..||...||   |....:|.|:||:.:
Mouse   256 FRKACDLVHNFTDAVIRERRHTLSSQ---------NHDEFLKSKTKSKTLDFIDVLLLAKDEHGK 311

  Fly   305 GLIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANI-DDELNILNIGQL 368
            .|.|. .|..|.||.||.|:|||:..|.:.|.|::.:||.||:|.||:|..: ..|...:....|
Mouse   312 ELSDE-DIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQELLRGREPQEIEWDDL 375

  Fly   369 NKLKNLEYFIKETMRLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSPEEF 433
            .:|..|...|||::||.|.|..:.|..||:..|.:|.::|||:...:.:|.||.||..|..||.:
Mouse   376 AQLPFLTMCIKESLRLHPPVIDLLRRCTRDIVLPDGRVIPKGNICVISIFGIHHNPSVWPDPEVY 440

  Fly   434 RPERFLPENSQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPE-----IDPKTI 493
            .|.||.|||:..|...|:||||||.||||||.|||.||...:...|.:|:|||:     ..|:.|
Mouse   441 DPFRFDPENAHKRPPLAFIPFSAGPRNCIGQTFAMNEMMVALALTLLRFRILPDDKEPRRKPEII 505

  Fly   494 V-FQTGLTLRTK 504
            : .:.||.||.:
Mouse   506 LRAEGGLWLRVE 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	150/467 (32%)
Cyp4f37	NP_001093657.1	CYP4F	74..515	CDD:410772	144/452 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845310
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D249473at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850