Protein Alignment Cyp4p3 and cyp46a1.3

DIOPT Version :10

• Sequence 1: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 529
• Identity: 126/529 - (23%)
• Similarity: 235/529 - (44%)
• Gaps: 67/529 - (12%)

  Fly     1 MLILWLVGAFIVLIQWIYRLNRDYCIL------GFFAKRIRTKNGQNPESIAPLVKGSTIFANSF 59
            :|:..::..|::...:|:.::..|..:      .||.       |.:| ::..|:|.:.:
 Frog    13 LLLALILICFLLFSGYIHYIHMKYDHIPGPPRDSFFL-------GHSP-TMLRLMKNNLL----- 64

  Fly    60 DLYGKDHSGVFEHSRDCAKKLGKSYAEYAMGTAIYNVIDADSAERVLNDPNLINKGTIYD----- 119
                     :::|.....:|.|.......:...|..|:..::.:.:|..|. .:|...||
 Frog    65 ---------MYDHFLGWVQKYGPVVRINGLHRVIILVVSPEAVKELLMSPK-YSKDKFYDVIANM 119

  Fly   120 FLHPFLRTGLLTSTG-KKWHARRKMLSP----TFHFNILNQFQEIFITESL--KFLEQFKGNDEA 177
            |...|:..||:|... ..||.:|:::.|    |:...::..|.|  ..|.|  |.:|:..|..|
 Frog   120 FGVRFMGKGLVTDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNE--KAEELMEKLMEKADGKCE- 181

  Fly   178 IISLNEVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFRQIEECFIRRMSNPLLWSDTLFKMFA 242
             |.:::::.|.||:.|.:.|.|::|:.:.:....:.:....:.:..: .|.||::......:.|.
 Frog   182 -IKMHDMLSRLTLDVIGKVAFGMELNSLNDDLTPFPKAISLVMKGIV-EMRNPMVRYSLAKRGFI 244

  Fly   243 EKDYASALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQTAEDELFTSKKRFAMLDTLILAEKDGLI 307
            .| ...::.::.....|.|.:|:.|:.|      ..:...|.|....|..||.:.   .:.:.|:
 Frog   245 RK-VQESIRLLRQTGKECIERRQKQIQD------GEEIPVDILTQILKGAAMEEE---CDPEILL 299

  Fly   308 DHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANIDDELNILNIGQLNKLK 372
            |:.      .|....|.:||:..|.|.:|.:...||..||...||...|..:.:| ....|.||:
 Frog   300 DNF------VTFFIAGQETTANQLSFVVMELGRNPEILEKAQAEIDEVIGSKRDI-EYEDLGKLQ 357

  Fly   373 NLEYFIKETMRLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSPEEFRPER 437
            .|...:|||:||:|:.|...|..| |..:.:|:.:|:...|.::.:.:.|..:|:..|..|.|:|
 Frog   358 YLSQVLKETLRLYPTAPGTSRGLT-EDMVIDGVKVPENVTIMLNSYIMGRMEQYYSDPLTFNPDR 421

  Fly   438 FLPENSQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTIVFQTGLTLR 502
            |.|:  ..:..|:|.|||.|.|:||||.|:..|.|.:|..||::::..........:..|| |||
 Frog   422 FSPD--APKPYYSYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRYEFELAEGQSFKILDTG-TLR 483

  Fly   503 TKNQIHVKL 511
            ..:.:..:|
 Frog   484 PLDGVICRL 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	CYP4	81..509	CDD:410721	113/439 (26%)
cyp46a1.3	NP_001027517.1	CYP46A1-like	66..490	CDD:410706	115/450 (26%)