Protein Alignment Cyp4p3 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001098671.1
• Gene: Cyp26c1 / 546726
• MGIID: 2679699
• Length: 518
• Species: Mus musculus
• Alignment Length: 554
• Identity: 124/554 - (22%)
• Similarity: 206/554 - (37%)
• Gaps: 143/554 - (25%)

  Fly     4 LWLVGAFIVLIQ--WIYR--LNRDYCILGFFAKRIRTKNGQNPESIAPLVKGSTIFANSFDLYGK 64
            |...|..:.|.|  |..|  |:||:.                  |..||.|||.    .:..:|:
Mouse    19 LLCAGLLLGLAQQLWTLRWTLSRDWA------------------STLPLPKGSM----GWPFFGE 61

  Fly    65 DHSGVFEHSR---DCAKKLGKSYAEYAMGTAIYNVIDADSAERVLNDPNLINKGTIYDFLHPFLR 126
            ....:.:.||   ...::.|..:..:.:|..:..|..|::...:|...:.:.:.......|..|.
Mouse    62 TLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLG 126

  Fly   127 T-GLLTSTGKKWHARRKMLSPTFHFNILNQFQEIFITESLKFLEQFKGNDEAIISLNEVIPRF-- 188
            : .||.:.|:....|||:|:..|               |...||||             :||.
Mouse   127 SHTLLGAVGEPHRQRRKVLARVF---------------SRSSLEQF-------------VPRLQG 163

  Fly   189 ----TLNSICETAMGVKLDEMAEKGDRYRENFR-----QIEECFIRRMSNPLLWSDTLFKMFAEK 244
                .:.|.|.....|.:.: |.|...:|...|     |::|.....:::       .|:...|.
Mouse   164 ALRREVRSWCAAQRPVAVYQ-AAKALTFRMAARILLGLQLDEARCTELAH-------TFEQLVEN 220

  Fly   245 DYASALDV-VHGFSSEIIAKRRDQLNDEIDSR-----GNTQTAE--DELFTSKKRFAMLDTLILA 301
            .::..||| ..|....|  :.||||.:.:|..     ...||||  |.|            |::.
Mouse   221 LFSLPLDVPFSGLRKGI--RARDQLYEHLDEAVAEKLQEKQTAEPGDAL------------LLII 271

  Fly   302 EKDGLIDHIGICEEVD----TLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQA-------- 354
            .....:.|....:|:.    .|:|..:.||:......::.:..:|....|..||:.|
Mouse   272 NSARELGHEPSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAITKIQQELSAQGLGRACT 336

  Fly   355 ------------NIDDELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETELSNGLIL 407
                        ..:.:|::..:|   :|:.::..:||.:||.|.|....|...|..|| :|..:
Mouse   337 CTPRASGSPPDCGCEPDLSLAMLG---RLRYVDCVVKEVLRLLPPVSGGYRTALRTFEL-DGYQI 397

  Fly   408 PKGSQIFVHVFDIHRNPEYWDSPEE-FRPERFLPENSQNRHT---YAYIPFSAGQRNCIGQKFAM 468
            |||..:...:.|.|.....:.||.| |.||||..|:...|.:   :.||||..|.|:|:||:.|.
Mouse   398 PKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESGDARGSGGRFHYIPFGGGARSCLGQELAQ 462

  Fly   469 QEMKTLMVALLKQ------------FQILPEIDP 490
            ..::.|.|.|::.            .|.:|.:.|
Mouse   463 AVLQLLAVELVRTARWELATPAFPVMQTVPIVHP 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	CYP4	81..509	CDD:410721	106/470 (23%)
Cyp26c1	NP_001098671.1	cytochrome_P450	59..504	CDD:477761	109/492 (22%)