Protein Alignment Cyp4p3 and Cyp49a1

DIOPT Version :10

• Sequence 1: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_610588.2
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Alignment Length: 576
• Identity: 124/576 - (21%)
• Similarity: 226/576 - (39%)
• Gaps: 133/576 - (23%)

  Fly    32 KRIRTKNGQNPESI----APLVKGSTIFANSFDLYGKDHSGVFEHSRDCAK--------KLGKSY 84
            :|:||....||:.:    .|:...:|....:..|..:..|......|..::        .:|.|:
  Fly    52 QRLRTGESSNPKKLNVSQQPVTSVATTRTTASSLPAETTSSPAAAVRPYSEVPGPYPLPLIGNSW 116

  Fly    85 AEYAMGTAIYNVIDADSAERVLNDPNLINKGTIY---------DFLH------------------ 122
             .:|.....|.:.|.|   :|:|:.: :|.|.:.         |.|.
  Fly   117 -RFAPLIGTYKISDLD---KVMNELH-VNYGKMAKVGGLIGHPDLLFVFDGDEIRNIFKKEEAMP 176

  Fly   123 -----PFLR--------------TGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIFITESLKFL 168
                 |.||              .||:...|.||.|.|:.:.   |..:..|..:.:|.......
  Fly   177 HRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWEAFRQEVQ---HILLQPQTAKKYIPPLNDIA 238

  Fly   169 EQFKGNDEAIISLNEVIP--------RFTLNSICETAMGVKLDEMAEKGDRYRENFRQIEECFIR 225
            .:|.|..|.:....:.:|        ::.|.|:...::..:|..::.:|.   |..:||.|..
  Fly   239 SEFMGRIELMRDEKDELPANFLHELYKWALESVGRVSLDTRLGCLSPEGS---EEAQQIIEAI-- 298

  Fly   226 RMSNPLLWS-------DTLFKMFAEKDYAS---ALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQT 280
               |...|:       ..|::::..|.|.|   |||.......:.|.|..|:. |..::||.:::
  Fly   299 ---NTFFWAVPELELRMPLWRIYPTKAYRSFVKALDQFTAICMKNIGKTMDKA-DADEARGLSKS 359

  Fly   281 AEDELF-------TSKKRFAMLDTLILAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNM 338
            ..|...       |..::.|.:..|                   .|...|.||||:.....:..:
  Fly   360 EADISIVERIVRKTGNRKLAAILAL-------------------DLFLVGVDTTSVAASSTIYQL 405

  Fly   339 SLYPEEQEKCYQEIQANIDDELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETELSN 403
            :..|::|:|.:.|:|.........:|...|.::..|...:|||:|:.|.|.|.||....:..: |
  Fly   406 AKNPDKQKKLFDELQKVFPHREADINQNVLEQMPYLRACVKETLRMRPVVIANGRSLQSDAVI-N 469

  Fly   404 GLILPKGSQ-IFVHVFDIHRNPEYWDSPEEFRPERFL---------PENSQNRHTYAYIPFSAGQ 458
            |..:|||:. ||.|:. :..:|.|:..|:.|.|||:|         |..:|..|.:..:||..|:
  Fly   470 GYHVPKGTHVIFPHLV-VSNDPAYFPEPKRFLPERWLKQSTDAAGCPHANQKIHPFVSLPFGFGR 533

  Fly   459 RNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTIVFQTGLTLRTKNQIHVKLVRR 514
            |.|:|::||..|:.||:..:.:::::  ..:....|::...|...::.::.||..|
  Fly   534 RMCVGRRFAEIELHTLLAKIFRKYKV--SYNSGEFVYRVNSTYIPQSPLNFKLTLR 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	CYP4	81..509	CDD:410721	111/508 (22%)
Cyp49a1	NP_610588.2	CYP24A1-like	138..581	CDD:410677	103/478 (22%)