Protein Alignment Cyp4p3 and cyp-13A7

DIOPT Version :10

• Sequence 1: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_496114.1
• Gene: cyp-13A7 / 188362
• WormBaseID: WBGene00000372
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 130/557 - (23%)
• Similarity: 222/557 - (39%)
• Gaps: 131/557 - (23%)

  Fly     3 ILWLVGAFIVLIQ---WIYRLNRDYCILGFFAKRIRTKNGQNPESIAPLVKGSTIFANSFDLYGK 64
            ||..:..|:.:|.   ||:         .|:.:    |..:.|..: |.:.....|.|      .
 Worm     5 ILIAIAIFVGIISYYLWIW---------SFWIR----KGVKGPRGL-PFLGVIHKFTN------Y 49

  Fly    65 DHSGVFEHSRDCAKKLGKSYAEYAMGTAIYNVIDADSAERVLNDPNLINKGTIYDFLHPF----- 124
            ::.|..:.| :..||.|          .:|.:.:......|::||..:::..:..|.:.:
 Worm    50 ENPGALKFS-EWTKKYG----------PVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGRKLT 103

  Fly   125 ---------LRTGLLTSTGKKWHARRKMLSPTFHFNILNQFQ---EIFITESLKFLEQFKGNDEA 177
                     .|..|:.:.|.:|...|.:.||||....|.:..   |..:||.::.||:.....:.
 Worm   104 AIQGDPNKNKRVPLVAAQGHRWKRLRTLASPTFSNKSLRKIMGTVEESVTELVRSLEKASAEGKT 168

  Fly   178 IISLNEVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFRQIEECFIRRMSNPLLWS-DTLFK-- 239
            :..| |....||::.|.:.|||      .||...:|               ||:|.. .|:||
 Worm   169 LDML-EYYQEFTMDIIGKMAMG------QEKSLMFR---------------NPMLDKVKTIFKEG 211

  Fly   240 --------------------MFAEKDYASALDVVHGFSSEIIAKRRDQLN-DE------------ 271
                                :||:.........:.....:.:.||.:|.. ||
 Worm   212 RNNVFMISGIFPFVGIALRNIFAKFPSLQMATDIQSILEKALNKRLEQREADEKAGIEPSGEPQD 276

  Fly   272 -----IDSRGNTQTAEDELFTSKKRFAMLDTLILAEKDGLIDHIGICEEVDTLMFEGYDTTSIGL 331
                 :|:|......|.|   :::.||..:.| ..:|....|.  |..::...:..|||||::.|
 Worm   277 FIDLFLDARSTVDFFEGE---AEQDFAKSEVL-KVDKHLTFDE--IIGQLFVFLLAGYDTTALSL 335

  Fly   332 MFGLMNMSLYPEEQEKCYQEIQANIDDELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETT 396
            .:....::.:||.|:|..:|:.....|.  .:...||:|||.||..:||.:||:|....:.....
 Worm   336 SYSSYLLATHPEIQKKLQEEVDRECPDP--EVTFDQLSKLKYLECVVKEALRLYPLASLVHNRKC 398

  Fly   397 RETELSNGLILPKGSQIFVHVFDIHRNPEYW-DSPEEFRPERFLPENSQNRHTYA---YIPFSAG 457
            .:|....|:.:..|:.|.|..:.:|.:|:.| |...||:|||:   .|.:...:|   |:||..|
 Worm   399 LKTTNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERW---ESGDELFFAKGGYLPFGMG 460

  Fly   458 QRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTIV 494
            .|.|||.:.||.|||.|:..:||.:..  |..|:|::
 Worm   461 PRICIGMRLAMMEMKMLLTNILKNYTF--ETTPETVI 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	CYP4	81..509	CDD:410721	114/476 (24%)
cyp-13A7	NP_496114.1	CYP3A-like	63..507	CDD:410678	115/478 (24%)