Protein Alignment Cyp4p3 and cyp-25A2

DIOPT Version :10

• Sequence 1: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 138/565 - (24%)
• Similarity: 225/565 - (39%)
• Gaps: 115/565 - (20%)

  Fly     1 MLILWLVGAFIVLIQWIYRLNRDYCILGFFAKR----IRTKNG-QNPESIAPLVKGSTIFANSFD 60
            |.:|.|....|:|:.:|        |...||:|    :|.|.| ..||.       .....|...
 Worm     1 MALLILTSILILLVSFI--------IYILFARREQFKLREKIGLTGPEP-------HWFMGNLKQ 50

  Fly    61 LYGKDHSGVFEHSRDCAKKLGKSYAE-------YAMGTAIYNVID---------ADSAERV---L 106
            :..:.....::.|.....:|.|.|.|       ..|...:.|..|         ::.::|:   :
 Worm    51 IVDRKEKLGYDDSNKWFNELHKQYGETFGIYFGAQMNIVLSNEEDIKEVFIKNFSNFSDRIVPPI 115

  Fly   107 NDPNLINKGTIYDFLHPFLRTGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIFITESLKFLE-- 169
            .|.|.:|:..:.:          ..:||  |...|..::|.|....:...||...::...||:
 Worm   116 FDSNQLNQSLLQN----------TYATG--WKHTRSAIAPIFSTGKMKAMQETIHSKVDLFLDIL 168

  Fly   170 QFKGNDEAIISLNEVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFRQ------------IEEC 222
            :.|.:......:.|.....||:.|.:.|..:..:...::.|.:..|.|:            |...
 Worm   169 REKASSGQKWDIYEDFQGLTLDVIGKCAFAIDSNCQRDRNDVFYVNARKFIANIDIRHSKVIAAS 233

  Fly   223 FIRRMSNPLLWSDTLFKMFAEKDYASALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQTAEDELFT 287
            ||.....| ||. .|:|.....|  :.:.:|.|.|:....:|..:.:|.:|
 Worm   234 FILPELAP-LWR-ALYKYTPLAD--AEIPLVEGLSNVYERRRGGEGSDSVD-------------- 280

  Fly   288 SKKRFAMLDTLILAEKDGL--IDHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQ 350
                  :|..|:..|.|..  :....:.|.....:..||:|||..:.:....:|.||..|:|.|:
 Worm   281 ------LLKLLLNREDDKSKPMTKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYE 339

  Fly   351 EIQANIDDELNILNIGQLNKLKNLEYFIKETMRLFPSV-PAMGRETTRETELSNGLILPKGSQIF 414
            ||..  ..|...|....::.:|.|:|..|||:|.:|.| ..:.|....:..: .|...||||.:.
 Worm   340 EIME--AKENGGLTYDSIHNMKYLDYVYKETLRCYPPVIHFINRRCLADITI-RGQFYPKGSVVT 401

  Fly   415 VHVFDIHRNPEYWDSPEEFRPERFLPEN-SQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVAL 478
            .....:|.|||.|||||||.||||  || .:...:..:|||..|.|.|:|.:||..|.||.:|.|
 Worm   402 CLPHTVHLNPENWDSPEEFHPERF--ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKL 464

  Fly   479 -----LKQFQ----ILPEIDPKTIVFQTGLTLRTKNQIHVKLVRR 514
                 ||||:    ::|:.:        |:.:|.|:.:.:.|..|
 Worm   465 LDTFELKQFKGEADLIPDCN--------GVIMRPKDPVRLLLKPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	CYP4	81..509	CDD:410721	118/473 (25%)
cyp-25A2	NP_497776.2	CYP3A-like	73..495	CDD:410678	117/470 (25%)