Protein Alignment Cyp4p3 and CYP4A11

DIOPT Version :9

• Sequence 1: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_000769.2
• Gene: CYP4A11 / 1579
• HGNCID: 2642
• Length: 519
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 137/441 - (31%)
• Similarity: 231/441 - (52%)
• Gaps: 42/441 - (9%)

  Fly    90 GTAIYNVIDADSAERVL--NDPNLINKGTIYDFLHPFLRTGLLTSTGKKWHARRKMLSPTFHFNI 152
            |.....:.|.|..:.:|  :||.  :.|: |.||.|::..|||...|:.|...|:||:|.||::|
Human    93 GKVRVQLYDPDYMKVILGRSDPK--SHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDI 154

  Fly   153 LNQFQEIFITESLKFL----EQFKGNDEAIISLNEVIPRFTLNSICETAM----GVKLDEMAEKG 209
            |..:..: :.:|::.:    |:..|.|.. :.:.:.:...||::|.:.|.    .:::|..::.
Human   155 LKPYVGL-MADSVRVMLDKWEELLGQDSP-LEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQS- 216

  Fly   210 DRYRENFRQIEECFIRRMSNPLLWSDTLFKMFAEKDYA-SALDVVHGFSSEIIAKRRDQLNDEID 273
              |.:....:......|:.|....:||::.:.:...:. .|..:.|..:.::|..|:.||..|
Human   217 --YIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKE-- 277

  Fly   274 SRGNTQTAEDELFTSKKRFAMLDTLILA--EKDGLIDHIGICEEVDTLMFEGYDTTSIGLMFGLM 336
                   .|.|....|:....||.|:||  |...::....:..||||.||||:|||:.|:.:.|.
Human   278 -------GELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILY 335

  Fly   337 NMSLYPEEQEKCYQEIQANIDDELNILNIGQLNKLKNLEY---FIKETMRLFPSVPAMGRETTRE 398
            .::.:|:.||:|.:||.:.:.|..:|    ..|.|..:.|   .|||.:||:|.||.:|||.:..
Human   336 ALATHPKHQERCREEIHSLLGDGASI----TWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTP 396

  Fly   399 TELSNGLILPKGSQIFVHVFDIHRNPEYWDSPEEFRPERFLPENSQNRHTYAYIPFSAGQRNCIG 463
            ....:|..||||..:.:.::.:|.||:.|.:||.|.|.||.|.::|  |::|::|||.|.|||||
Human   397 VTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRNCIG 459

  Fly   464 QKFAMQEMKTLMVALLKQFQILPEIDPKTIVFQTG-LTLRTKNQIHVKLVR 513
            ::|||.|:|......|.:|::||  ||..|..... |.|::||.||::|.|
Human   460 KQFAMNELKVATALTLLRFELLP--DPTRIPIPIARLVLKSKNGIHLRLRR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	131/431 (30%)
CYP4A11	NP_000769.2	p450	52..505	CDD:278495	135/436 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154852
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850