Protein Alignment Cyp4p3 and Cyp4a14

DIOPT Version :10

• Sequence 1: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Alignment Length: 433
• Identity: 134/433 - (30%)
• Similarity: 229/433 - (52%)
• Gaps: 46/433 - (10%)

  Fly    98 DADSAERVL--NDPNLINKGTIYDFLHPFLRTGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIF 160
            |.|..:.||  :||   ....||.|..|::..|||...||||...|:||:|.||::||..:.:|
Mouse    98 DPDYVKVVLGRSDP---KASGIYQFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKI- 158

  Fly   161 ITESLKFL----EQFKGNDEAIISLNEVIPRFTLNSICETAM----GVKLDEMAEKGDRYRENFR 217
            :.:|:..:    |:..|.|.. :.:...:...||:::.:.|.    .|:|||.::   .|.:...
Mouse   159 MADSVNIMLDKWEKLDGQDHP-LEIFHCVSLMTLDTVMKCAFSYQGSVQLDENSK---LYTKAVE 219

  Fly   218 QIEECFIRRMSNPLLWSDTLFKMFAEKDYA-SALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQTA 281
            .:......|:.|.....:.::.|.::...: .|..:.|..:..:|..|:.||.:
Mouse   220 DLNNLTFFRLRNAFYKYNIIYNMSSDGRLSHHACQIAHEHTDGVIKMRKSQLQN----------- 273

  Fly   282 EDELFTSKKR--FAMLDTLILA---EKDGLIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLY 341
            |:||..::|:  ...||.|:.|   :::.|.|. .:..||||.||||:|||:.|:.:....::.:
Mouse   274 EEELQKARKKRHLDFLDILLFARMEDRNSLSDE-DLRAEVDTFMFEGHDTTASGISWIFYALATH 337

  Fly   342 PEEQEKCYQEIQANIDDELNIL--NIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETELSNG 404
            ||.|::|.:|:|:.:.|..::.  ::||   :......|||.:||:|.|.::.||.:......:|
Mouse   338 PEHQQRCREEVQSILGDGTSVTWDHLGQ---MPYTTMCIKEALRLYPPVISVSRELSSPVTFPDG 399

  Fly   405 LILPKGSQIFVHVFDIHRNPEYWDSPEEFRPERFLPENSQNRHTYAYIPFSAGQRNCIGQKFAMQ 469
            ..:|||....:.::.:|.||.:|.:|:.|.|.||.|::|  .|::||:|||.|.|||||::|||.
Mouse   400 RSIPKGITATISIYGLHHNPRFWPNPKVFDPSRFAPDSS--HHSHAYLPFSGGSRNCIGKQFAMN 462

  Fly   470 EMKTLMVALLKQFQILPEIDPKTI-VFQTGLTLRTKNQIHVKL 511
            |:|..:...|.:|::||  ||..| |....|.|::||.||:.|
Mouse   463 ELKVAVALTLLRFELLP--DPTRIPVPIARLVLKSKNGIHLCL 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	CYP4	81..509	CDD:410721	132/429 (31%)
Cyp4a14	NP_031848.1	CYP4B-like	69..502	CDD:410771	133/430 (31%)