Protein Alignment Cyp4p3 and Cyp4a12b

DIOPT Version :10

• Sequence 1: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Alignment Length: 459
• Identity: 144/459 - (31%)
• Similarity: 237/459 - (51%)
• Gaps: 57/459 - (12%)

  Fly    78 KKLGKSYAEYAMGTAI-YNVIDADSAERVL--NDPNLINKGTIYDFLHPFLRTGLLTSTGKKWHA 139
            |....:..::..|:.: ..|.|.|..:.:|  :||.....   |.||.|::..|||...|:.|..
Mouse    78 KNFPSACPQWLWGSKVRIQVYDPDYMKLILGRSDPKAHGS---YRFLAPWIGRGLLLLDGQTWFQ 139

  Fly   140 RRKMLSPTFHFNILNQFQEIFITESLKFL----EQFKGNDEAIISLNEVIPRFTLNSICETAM-- 198
            .|:||:|.||::||..:.|| :.:|:..:    ||..|.| :.:.:.:.|...||::|.:.|.
Mouse   140 HRRMLTPAFHYDILKPYTEI-MADSVHVMLDKWEQIVGQD-STLEIFQHITLMTLDTIMKCAFSH 202

  Fly   199 --GVKLDEMAEKGDRYRENFRQIEE---CFIRRMSNPLLWSDTLFKMFAEKDYA-SALDVVHGFS 257
              .|:||.      :|:...:.:|:   .|..|:.|....:|.::::.:....| ||..:.|..:
Mouse   203 EGSVQLDR------KYKSYIQAVEDLNNLFFLRVRNIFHQNDIIYRVSSNGCLANSACQLAHDHT 261

  Fly   258 SEIIAKRRDQLNDEIDSRGNTQTAEDELFTSKKRFAMLDTLI---------LAEKDGLIDHIGIC 313
            .::|..||.||.||         .|.|....|:|...||.|:         |::||       :.
Mouse   262 DQVIKSRRSQLQDE---------EELEKLKKKRRLDFLDILLFARMENGKSLSDKD-------LR 310

  Fly   314 EEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANIDDELNILNIGQLNKLKNLEYFI 378
            .||||.||||:|||:.|:.:....::..||.|::|.:|||:.:.|..:| ....|:|:......|
Mouse   311 AEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLGDGASI-TWNDLDKMPYTTMCI 374

  Fly   379 KETMRLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSPEEFRPERFLPENS 443
            ||.:|::|.||::.||.:......:|..||||..:.:..:.:|.||..|.:||.|.|.||.|.:|
Mouse   375 KEALRIYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVWPNPEVFDPSRFAPGSS 439

  Fly   444 QNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTIVFQ-TGLTLRTKNQI 507
              ||:::::|||.|.|||||::|||.|:|..:...|.:|::||  ||..:... ..:.|::||.|
Mouse   440 --RHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP--DPTRVPIPIPRIVLKSKNGI 500

  Fly   508 HVKL 511
            |:.|
Mouse   501 HLHL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	CYP4	81..509	CDD:410721	141/452 (31%)
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	143/456 (31%)