Protein Alignment Cyp4p3 and Cyp46a1

DIOPT Version :9

• Sequence 1: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Alignment Length: 461
• Identity: 110/461 - (23%)
• Similarity: 207/461 - (44%)
• Gaps: 90/461 - (19%)

  Fly    70 FEHSRDCAKKLGKSYAEYA--MGTAI-YNVIDADSAERVLNDPNLINK---GTIYD---FLHPFL 125
            ::...||.:.|...:.::|  .|..: .||....|.  ::..|..:.|   .|.|:   .::..|
Mouse    50 WKKDEDCGRVLQDVFLDWAKKYGPVVRVNVFYKTSV--IVTSPESVKKFLMSTKYNKDSKMYRAL 112

  Fly   126 RT---------GLLTSTG-KKWHARRKMLSPTFHFNILNQFQEIFITESLKFLE--QFKGNDEAI 178
            :|         ||::... .:|:.:||::...|..:.|....|.|..::.:.:|  :.|.:.:..
Mouse   113 QTVFGERLFGQGLVSECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTP 177

  Fly   179 ISLNEVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFRQIEECFIRRMSNPLLWSDTLFKMFAE 243
            :|:.:::...|::.:.:.|.|:                                  :|...:.|:
Mouse   178 VSMQDMLTCATIDILAKAAFGM----------------------------------ETSMLLGAQ 208

  Fly   244 KDYASALDV-VHGFSS--EIIAK----RRDQLNDEIDS-RGNTQTAEDELFTSKKRFAM------ 294
            |..:.|:.| :.|.|:  ..:||    :|.||.:..:| |...|..:|  :..::|.|:
Mouse   209 KPLSQAVKVMLEGISASRNTLAKFMPGKRKQLREIRESIRLLRQVGKD--WVQRRREALKRGEDM 271

  Fly   295 ---LDTLILAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANI 356
               :.|.||..::|..|...:.:...|....|::|::..|.|.:|.:|..||    ....:||.:
Mouse   272 PADILTQILKAEEGAQDDEVLLDNFVTFFIAGHETSANHLAFTVMELSRQPE----IVARLQAEV 332

  Fly   357 DDELNI---LNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETE-LSNGLILPKGSQIFVHV 417
            |:.:..   |:...|.:|:.|...:||::||:|  ||.|.....|.| |.:|:.:|..:.:....
Mouse   333 DEVVGSKRHLDYEDLGRLQYLSQVLKESLRLYP--PAWGTFRLLEEETLIDGVRVPGNTPLLFST 395

  Fly   418 FDIHRNPEYWDSPEEFRPERFLPENSQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLK-- 480
            :.:.|...|::.|..|.|:||.|...:.|.|  |.|||.|.|:||||:||..|:|.:|..||:
Mouse   396 YVMGRMDTYFEDPLTFNPDRFGPGAPKPRFT--YFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRI 458

  Fly   481 QFQILP 486
            :|:::|
Mouse   459 EFRLVP 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	110/461 (24%)
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	110/461 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000