Protein Alignment Cyp4p3 and CYP4F22

DIOPT Version :10

• Sequence 1: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_775754.2
• Gene: CYP4F22 / 126410
• HGNCID: 26820
• Length: 531
• Species: Homo sapiens
• Alignment Length: 407
• Identity: 143/407 - (35%)
• Similarity: 216/407 - (53%)
• Gaps: 28/407 - (6%)

  Fly   118 YDFLHPFLRTGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIFITES----LKFLEQFKGNDEAI 178
            |.||.|:|..|||.|.|.||...|::|:|.|||:||..:.:||...:    .|:....:|   :.
Human   133 YGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEG---SA 194

  Fly   179 ISLN--EVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFRQIEECFIRRMSNPLLWSDTLFKMF 241
            :||:  |.|...||:|:.:...... ....||...|.....::....:||......:.|.::...
Human   195 VSLDMFEHISLMTLDSLQKCVFSYN-SNCQEKMSDYISAIIELSALSVRRQYRLHHYLDFIYYRS 258

  Fly   242 AE-KDYASALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQTAEDELFTSK-KRFAMLDTLILA-EK 303
            |: :.:..|.|:||.|::|:|.:||..|..        |.||..|...: |....:|.|:|| ::
Human   259 ADGRRFRQACDMVHHFTTEVIQERRRALRQ--------QGAEAWLKAKQGKTLDFIDVLLLARDE 315

  Fly   304 DG--LIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANIDD-ELNILNI 365
            ||  |.|. .|..|.||.||||:||||.|:.:.|.|::.|||.||||.:|||..:.. ||..|..
Human   316 DGKELSDE-DIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEW 379

  Fly   366 GQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSP 430
            ..|.:|......|||::|.:|.|..:.|:.|.:.:|.:|.|:|||....|.::..|.||..|...
Human   380 DDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDS 444

  Fly   431 EEFRPERFLPENSQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEID-PKTIV 494
            :.:.|.||.|:|.|.|...||:|||||.||||||.|||.|::.::...|.:|::  .:| .:.:.
Human   445 KVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRL--SVDRTRKVR 507

  Fly   495 FQTGLTLRTKNQIHVKL 511
            .:..|.|||:|.:.:|:
Human   508 RKPELILRTENGLWLKV 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	CYP4	81..509	CDD:410721	142/403 (35%)
CYP4F22	NP_775754.2	CYP4F	82..523	CDD:410772	142/404 (35%)