DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p3 and cyp2p7

DIOPT Version :9

Sequence 1:	NP_610473.1	Gene:	Cyp4p3 / 35948	FlyBaseID:	FBgn0033397	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001076518.1	Gene:	cyp2p7 / 100034406	ZFINID:	ZDB-GENE-041001-155	Length:	496	Species:	Danio rerio

Alignment Length:	513	Identity:	121/513 - (23%)
Similarity:	199/513 - (38%)	Gaps:	113/513 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 FFAKRIRTKNGQN----PESIAPLVKGSTIFANSFDLYGKDHSGVFEHSRDCAKKLGKSYAEYAM 89
            |.:..||.|:.:|    |.|: |.:.         .::..:|..|.......|:|.||.::....
Zfish    24 FLSDYIRNKSPKNFPPGPWSL-PFIG---------HIHHIEHKKVHLQFLKFAEKYGKIFSIRLF 78

  Fly    90 GTAIYNVIDADSAER---VLNDPNLINKGTI---YDFLHPFLRTGLLTSTGKKW-HARRKMLSPT 147
            |..|. |:|.....:   :....||.::..:   ||....   .||:.|.|.|| |.||..||..
Zfish    79 GPRIV-VLDGYKLVKEVYLQQGDNLADRPILPMFYDITED---KGLIGSNGYKWKHQRRFALSTF 139

  Fly   148 FHFNILNQFQEIFITESLKFLEQFKGNDEAIISLNEVIPRFTLNS-----ICETAMGVKLDEMAE 207
            ..|.:..:..|..|......|.....|::.    ....||..||:     ||......:.|
Zfish   140 RTFGLGKKSLEPSILLECSCLNDAFSNEQG----RPFDPRLLLNNAVSNVICALVFSNRFD---- 196

  Fly   208 KGDRYRENFRQIEECFIRRMSNPL-----LWSDTLFKMFA----------EKDYASALDVVHGFS 257
                |.::..|   ..::.::..|     :|:. |:..|.          :|.:. .|:.|..|.
Zfish   197 ----YSDHHFQ---TLLKHINEVLYLEGTVWAQ-LYNFFPWLMRRLPGPHQKIFV-LLNKVIDFV 252

  Fly   258 SEIIAKRR---DQLN--DEIDSRGNTQTAEDELFTSKKRFAMLDTLILAEKDGL---------ID 308
            .|.:.:.|   |..|  |.||                        ..|||.:.|         ::
Zfish   253 REKVNEHRVDYDPSNPRDYID------------------------CFLAEMEKLKDDTAAGFDVE 293

  Fly   309 HIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANIDDELNILNIGQLNKLKN 373
            ::.|| .:| |...|.:|||..|.:||:.:..|||.|.|..|||.|.:.....    ..::...|
Zfish   294 NLCIC-TLD-LFVAGTETTSTTLYWGLLYIIKYPEIQAKVQQEIDAVVGGSRQ----PSVSDRDN 352

  Fly   374 LEY---FIKETMRLFPSVPA-MGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSPEEFR 434
            :.|   .|.|..|:...||. :.|.|..:|::.. ..:|||:.:...:..:..:...|::|..|.
Zfish   353 MPYTNAVIHEIQRMGNIVPLNVFRITVEDTQIGE-YSIPKGTLVIGSLTSVLFDESEWETPHSFN 416

  Fly   435 PERFLPENSQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPE--IDP 490
            |..||....:.|...|::|||.|:|.|:|::.|..|:.....:||::|...|.  ::|
Zfish   417 PGHFLDAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEP 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p3	NP_610473.1	p450	54..505	CDD:278495	113/484 (23%)
cyp2p7	NP_001076518.1	p450	38..492	CDD:278495	116/499 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010