DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p2 and CYP704B1

DIOPT Version :9

Sequence 1:	NP_610472.1	Gene:	Cyp4p2 / 35946	FlyBaseID:	FBgn0033395	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_177109.3	Gene:	CYP704B1 / 843283	AraportID:	AT1G69500	Length:	524	Species:	Arabidopsis thaliana

Alignment Length:	586	Identity:	138/586 - (23%)
Similarity:	233/586 - (39%)	Gaps:	130/586 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MMICLLWISVAILVVIHWIYKVNKDYNILAFFARRVQTKDGKPLDSLV-PMIKGRTVFANCFDLL 64
            |.:||    |...:|..||:        |..:.:|  .|.|.....|| ..|:..|.|....|.|
plant     1 MSLCL----VIACMVTSWIF--------LHRWGQR--NKSGPKTWPLVGAAIEQLTNFDRMHDWL 51

  Fly    65 GKDTDQVFTHLRQLAKNSGDSYLQYS------MGFSNFNVI-DAHNA-----ANILNHPNLITKG 117
            .:                   ||..|      |.|:.:..| |..|.     .|..|:|    ||
plant    52 VE-------------------YLYNSRTVVVPMPFTTYTYIADPINVEYVLKTNFSNYP----KG 93

  Fly   118 VIY-NFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAE-SLK---FVSQ--FQG 175
            ..| :::...|..|:..:..:.|..:|...:..|....|..|..:...| |||   .:||  |:.
plant    94 ETYHSYMEVLLGDGIFNSDGELWRKQRKTASFEFASKNLRDFSTVVFKEYSLKLFTILSQASFKE 158

  Fly   176 QNEVVVSLKDRISRFTLNSICETAMGIKLDEMAEK--GDRYRANFHIIDEGLTRRIVNPLYWDDC 238
            |.   |.:::.:.|.||:|||:...|:::..:|.:  .:.:...|...:..:|.|.::||:....
plant   159 QQ---VDMQELLMRMTLDSICKVGFGVEIGTLAPELPENHFAKAFDTANIIVTLRFIDPLWKMKK 220

  Fly   239 VYNMFTGHKYNAALKVVHEFSREIIAKRRV-LLEEEL----ENRRATQTADDDICVIRKKRFAML 298
            ..|:.:......::|||::|:..:|.:|:. |||.::    .|.........||.    .||
plant   221 FLNIGSEALLGKSIKVVNDFTYSVIRRRKAELLEAQISPTNNNNNNNNKVKHDIL----SRF--- 278

  Fly   299 DTLICAEKDGLIDDIGISEEVDTLMAE-------------GYDTTSIGLVFGLMNMSLYAAEQEL 350
                          |.||::.|:...|             |.|||:..|.:.:..:.:.....|.
plant   279 --------------IEISDDPDSKETEKSLRDIVLNFVIAGRDTTATTLTWAIYMIMMNENVAEK 329

  Fly   351 CYQEIQE-------------HILD--DLSN-----------LNLSQLSKLNYLGYFIKETMRLYP 389
            .|.|:||             |..|  |.::           ||...|.||:||...|.||:||||
plant   330 LYSELQELEKESAEATNTSLHQYDTEDFNSFNEKVTEFAGLLNYDSLGKLHYLHAVITETLRLYP 394

  Fly   390 SIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYWESPEE-FRPERFLPQNCLKR-HPY 452
            ::|...:..|::..|.||..:.....:....:.:.|....|.|... |:|||:|.....:. .|:
plant   395 AVPQDPKGVLEDDMLPNGTKVKAGGMVTYVPYSMGRMEYNWGSDAALFKPERWLKDGVFQNASPF 459

  Fly   453 AYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQVGITLRFKNKIKVKLVRR 517
            .:..|.||.|.|:|:..|..:||..|.::.:.:| ..::....:.:::...|...:.:||.:.||
plant   460 KFTAFQAGPRICLGKDSAYLQMKMAMAILCRFYK-FHLVPNHPVKYRMMTILSMAHGLKVTVSRR 523

  Fly   518 N 518
            :
plant   524 S 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	119/517 (23%)
CYP704B1	NP_177109.3	PLN03195	1..524	CDD:215627	137/584 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920