DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p2 and CYP96A2

DIOPT Version :9

Sequence 1:	NP_610472.1	Gene:	Cyp4p2 / 35946	FlyBaseID:	FBgn0033395	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_194944.1	Gene:	CYP96A2 / 829349	AraportID:	AT4G32170	Length:	506	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	126/557 - (22%)
Similarity:	228/557 - (40%)	Gaps:	99/557 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ICLLWISVAIL--VVIHW-IYKVNKDYNILAFFARRVQTKDGKP----------LDSLVPMIKGR 54
            |.||.:|||||  :::|: ::|                    ||          |..|..|:|.
plant     4 ISLLQVSVAILCFLILHYFLFK--------------------KPHGRYPRNWPVLRMLPAMLKA- 47

  Fly    55 TVFANCFDLLGKDTDQVFTHLRQLAKNSGDSYLQYSMGFSNFNVIDAHNAANI-----LNHPNLI 114
                         ..:::.:..::.:.|..::......|:..:::...:.|||     .|..|.|
plant    48 -------------LHRIYDYSVKILETSDLTFPFKGPRFTGMDMLLTVDPANIHHIMSSNFSNYI 99

  Fly   115 TKGVIYNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLKF-----VSQFQ 174
             ||..:..:...|....:|...:.|...|.......|.....:|....:...||:     ::.|
plant   100 -KGPEFQDVFDVLGDSFITTDSELWKNMRKSYQAMLHSQEFQRFSMSTMTSKLKYGLVPLLNHF- 162

  Fly   175 GQNEVVVSLKDRISRFTLNSIC-------ETAMGIKLDEMAEKGDRYRANFHIIDEGLTRRIVNP 232
            .:....:.|:....|||.::|.       ..::.|::.|     |.:......:.||:..|...|
plant   163 AEEGTTLDLQSVFGRFTFDTIFILVTGSDPRSLSIEMPE-----DEFAKALDDVGEGILYRHFKP 222

  Fly   233 LY-WDDCVYNMFTGHKYNAALKVVHEFSREIIAKRRVLLEEELENRRATQT-ADDDICVIRKKRF 295
            .: |.   ...:.|......|...:.....:.||......||::..:.|.. ...|:..    .|
plant   223 RFLWK---LQNWIGFGQEKKLTEANATFDRVCAKYISAKREEIKRSQGTSNGGSQDLLT----SF 280

  Fly   296 AMLDTLICAEKDGLI---DDIGISEEVDTLMAEGYDTTSIGL--VFGLMNMSLYAAEQELCYQEI 355
            ..|||    .|..|:   ||..:.:.:...:..|.|||:..|  .|.|::.:.:...:  .:|||
plant   281 IKLDT----TKYKLLNPSDDKFLRDNILAFILAGRDTTATALSWFFWLLSENPHVVAK--IHQEI 339

  Fly   356 QEHILDDLSNLNLSQ--LSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINI 418
              :|..|||....||  :.||.||...:.|.|||||.:....:..::...|.:|..:...|:|.|
plant   340 --NINTDLSRTGNSQENVDKLVYLHGALCEAMRLYPPVSFGRKSPIKSDVLPSGHKVDANSKIII 402

  Fly   419 HVFDIHRNPKYW-ESPEEFRPERFLPQN-CLKRHP-YAYIPFSAGQRNCIGQKYAMQEMKTLMVV 480
            .::.:.|....| |...:|:|||::.:| .:|..| :.::.|:||.|.|:|:..||.:||.:.|.
plant   403 CLYALGRMRAVWGEDASQFKPERWISENGGIKHEPSFKFLSFNAGPRTCLGKHLAMTQMKIVAVE 467

  Fly   481 ILKHFKILPVIDPKSIVFQVGITLRFKNKIKVKLVRR 517
            ||:::.| .|:..:.||..:|..|..|:.:::.:.:|
plant   468 ILRNYDI-KVLQGQKIVPALGFILSMKHGLQITVTKR 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	109/479 (23%)
CYP96A2	NP_194944.1	p450	1..503	CDD:416425	125/555 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010