DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4p2 and CYP86A8

DIOPT Version :9

Sequence 1:	NP_610472.1	Gene:	Cyp4p2 / 35946	FlyBaseID:	FBgn0033395	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_182121.1	Gene:	CYP86A8 / 819205	AraportID:	AT2G45970	Length:	537	Species:	Arabidopsis thaliana

Alignment Length:	466	Identity:	104/466 - (22%)
Similarity:	195/466 - (41%)	Gaps:	87/466 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 DAHNAANIL-----NHPNLITKGVIYNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQ 159
            |..|..:||     |:|...|...::   |..|..|:..:....|..:|......|....|.|..
plant    86 DPRNLEHILKNRFDNYPKGPTWQAVF---HDLLGQGIFNSDGDTWLFQRKTAALEFTTRTLRQAM 147

  Fly   160 EIFI--AESLKFVSQFQGQ--NEVVVSLKDRISRFTLNSIC---------ETAMGIKLDEMAEKG 211
            ..::  |..|:|:...:..  ....:.|:|.:.|.|.::||         ..|.|:.::..|...
plant   148 ARWVNRAIKLRFLPILENARLGSEPIDLQDLLLRLTFDNICGLTFGKDPRTCAPGLPVNTFAVAF 212

  Fly   212 DRYRANFHIIDEGLTRRIVNPLYWDDCVYNMFTGHKYNAALKV------------VHEFSREIIA 264
            ||      ..:..|.|.|:..:.|           |:...|::            |..:..|||.
plant   213 DR------ATEASLQRFILPEILW-----------KFKRWLRLGLEVSLTRSLVQVDNYLSEIIT 260

  Fly   265 KRRVLLEEELENRRATQTADDDIC--VIRKKRFAMLDTLICAEKDGLIDDIGISEEVDTLMAEGY 327
            .|:    ||:..:.......||:.  .|:||.         :..|..:..:.::     .:..|.
plant   261 TRK----EEMMTQHNNGKHHDDLLSRFIKKKE---------SYSDETLQRVALN-----FILAGR 307

  Fly   328 DTTSIGLVFGLMNMSLYAAEQELCYQEIQEHIL----DDLS-----NLNLSQLSKLNYLGYFIKE 383
            ||:|:.|.:....::.:.|.::...:||...::    ||::     .|:..:|.:|.:|...:.|
plant   308 DTSSVALSWFFWLITQHPAIEDKILREICTVLVETRGDDVALWTDEPLSCEELDRLVFLKAALSE 372

  Fly   384 TMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYW-ESPEEFRPERFLPQN-- 445
            |:|||||:|...::.:::..|.:|..:|..|.|...::...|....| |...||:|||::.|:
plant   373 TLRLYPSVPEDSKRAVKDDVLPDGTFVPAGSSITYSIYSAGRMKSTWGEDCLEFKPERWISQSDG 437

  Fly   446 --CLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTL-MVVILKHFKILPVIDPKSIVFQVGITLRFK 507
              .:...|:.::.|:||.|.|:|:..|..:||:: ..|:|:|  .|.|:....:..::.:||..|
plant   438 GRFINHDPFKFVAFNAGPRICLGKDLAYLQMKSIASAVLLRH--RLTVVTGHKVEQKMSLTLFMK 500

  Fly   508 NKIKVKLVRRN 518
            ..:.|.:..|:
plant   501 YGLLVNVHERD 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	103/460 (22%)
CYP86A8	NP_182121.1	CYP86A	67..503	CDD:410687	102/456 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010