Protein Alignment Cyp4p2 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001038763.1
• Gene: cyp46a1.3 / 692332
• ZFINID: ZDB-GENE-060519-40
• Length: 491
• Species: Danio rerio
• Alignment Length: 514
• Identity: 116/514 - (22%)
• Similarity: 205/514 - (39%)
• Gaps: 84/514 - (16%)

  Fly     8 ISVAILVVIHWIYKVNKDYNILAFFARRVQTKDGKPLDSL----VPMIKGRTVFANCFDLLGKDT 68
            :.|..|....:|::|::.|:.:          .|.|.|:.    :|.|...|
Zfish    17 VFVVFLAYCLYIHQVHQKYDHI----------PGPPRDNFLLGHIPTINRVT------------- 58

  Fly    69 DQVFTHLRQL----AKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITKGVIYN-----FLH 124
             :...|:..|    |:..|..|...|..:...||........|:..|..:....||.     |..
Zfish    59 -KSERHMNDLLLIWAEKYGPVYRLNSFHYVIINVHCPEATKTIMMSPKYLKDPFIYKRLFGLFGK 122

  Fly   125 PFLRTGVLTATEKK-WHTRRSMLTRTFHLDILNQFQEIFIAESLKFVSQFQGQ--NEVVVSLKDR 186
            .||..|::|||:.. |:.:|.::...|....|......|...|.:.:.:.:..  |:....:.|.
Zfish   123 RFLGYGLVTATDHDIWYRQRRIMDPAFSSSYLRGLISTFNEMSERLMDKLEEMAINKTPAVMHDL 187

  Fly   187 ISRFTLNSICETAMGIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDCVY---NMFTGHKY 248
            ::..||:.||:.|.|:.|:...:..:.::.......:|:...:.:|.    |.:   |.....:.
Zfish   188 VNCVTLDIICKVAFGVDLNLFKQTDNPFQQAIEQCLQGMVLDLRDPF----CKFFPKNWKAIQET 248

  Fly   249 NAALKVVHEFSREIIAKRRVLLE--EELENRRATQ---TADDDICVIRKKRFAMLDTLICAEKDG 308
            ..|..::.:...:.|..|:..:|  |::.|...||   ||.::.....|....|||..:
Zfish   249 KGATVLLRKTGEQWIQNRKTAVEIGEDVPNDILTQILKTAKEEKVNNTKDHEQMLDNFV------ 307

  Fly   309 LIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSNLNLSQLSK 373
                        |....|.:||:..|.|.:|.:..:....:....|:.| :|....:::...|.|
Zfish   308 ------------TFFIAGQETTANQLSFAIMELGRHPEIYKRAKAEVDE-VLGTKRDISYEDLGK 359

  Fly   374 LNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYWESPEEFRP 438
            ..||...:|||:||||:.|...| .|.|..:.||:.:|....:....:...|..|:::.|.:|.|
Zfish   360 FTYLSQVLKETLRLYPTAPGTNR-WLHEDMVINGIKIPGGISVIFSSYVAQRLEKHFKDPLKFDP 423

  Fly   439 ERFLPQNCLKRHP-YAYIPFSAGQRNCIGQKY--------AMQEMKTLMVVILKHFKIL 488
            |||   |.....| |.|.|||.|.|:|:||.:        |:.::.|.::.:..||.|:
Zfish   424 ERF---NVNAPKPYYCYYPFSLGPRSCLGQVFSQATPAEGALAQLLTQLLTLCSHFLIV 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	105/455 (23%)
cyp46a1.3	NP_001038763.1	p450	39..452	CDD:278495	106/453 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010