Protein Alignment Cyp4p2 and Cyp4a31

DIOPT Version :10

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_964002.2
• Gene: Cyp4a31 / 666168
• MGIID: 3028580
• Length: 509
• Species: Mus musculus
• Alignment Length: 547
• Identity: 148/547 - (27%)
• Similarity: 251/547 - (45%)
• Gaps: 99/547 - (18%)

  Fly     2 MICLLWISV-AILVVIH--WIYKVNKDYNILAF--FARRVQTKDGKPLDSLVPMIK--------- 52
            :.|||.:.| |:.|.:|  |:.|..:.:....|  |....|.|..:.|..:|..|:
Mouse    24 VFCLLLLLVKAVQVYLHRKWLLKALQQFPSPPFHWFFGHEQFKGDQELQEIVSCIENFPSAFPRW 88

  Fly    53 --GRTVFANCFDLLGKDTDQVFTHLRQLAKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLIT 115
              |...:...:|                     ..|::..:|.|:    ...|.|
Mouse    89 FWGSKAYLTVYD---------------------PDYMKVILGRSD----PKANGA---------- 118

  Fly   116 KGVIYNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLKFV----SQFQGQ 176
                |..|.|::..|:|....:.|...|.|||..||.|||..:.: .:|:|::.:    .:..||
Mouse   119 ----YRLLAPWIGYGLLLLNGQSWFQHRKMLTPAFHYDILKTYVK-NMADSIRLMLDKWERLAGQ 178

  Fly   177 NEVVVSLKDRISRFTLNSICETAMGIKLDEMAEKGD-----RYRANFHIIDE--GLTR-RIVNPL 233
            :. .:.:...||..||:::.:.|       .:.||.     .|:.....|.:  .|.. |:.|..
Mouse   179 DS-SIEIFQHISLMTLDTVMKCA-------FSHKGSVQVDGNYKTYLQAIGDLNNLVHSRVRNMF 235

  Fly   234 YWDDCVYNMFT-GHKYNAALKVVHEFSREIIAKRRVLLEE--ELENRRATQTADDDICVIRKKRF 295
            :.:|.:|.:.: |...|.|.::.|:.:..:|..|:..|::  ||||            :.:|:|.
Mouse   236 HQNDTIYKLSSNGRLSNQACQLAHDHTDGVIKMRKDQLQDEGELEN------------IKKKRRL 288

  Fly   296 AMLDTLICA--EKDGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEH 358
            ..||.|:.|  |.:..:.|..:..||||.|.||:|||:.|:.:....::.:...|:.|.:|:|.
Mouse   289 DFLDILLFARMENEDSMSDKDLRAEVDTFMIEGHDTTASGVSWIFYALATHPEHQQRCREEVQS- 352

  Fly   359 ILDDLSNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDI 423
            :|.|.|::....|.::.|....|||.:||||.:|.:||:........:|..|||..|:.:.::.:
Mouse   353 LLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPSIGRELSTSVTFPDGCSLPKGVQVTLSIYGL 417

  Fly   424 HRNPKYWESPEEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKIL 488
            |.|||.|.:||.|.|.||.|.:  .||.::::|||.|.|||||:::||.|:|.::.:.|..|::|
Mouse   418 HHNPKVWPNPEVFDPSRFAPDS--PRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELL 480

  Fly   489 PVIDPKSIVFQVG-ITLRFKNKIKVKL 514
            |  ||..:...:. ..|:.||.|.:.|
Mouse   481 P--DPTRVPMSLARFVLKSKNGIYLHL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	CYP4	83..512	CDD:410721	129/446 (29%)
Cyp4a31	NP_964002.2	CYP4B-like	71..504	CDD:410771	134/497 (27%)