Protein Alignment Cyp4p2 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 555
• Identity: 122/555 - (21%)
• Similarity: 229/555 - (41%)
• Gaps: 110/555 - (19%)

  Fly     2 MICLLWISVAILVVIHWIYKVNKDYNILAFFARRVQTKDGKPLDSLVPMIKGRTVFANCFDLLGK 66
            ::.|..|.:..|:...:|:.::..|:.:          .|.|.||.               .||.
 Frog    12 LLLLALILICFLLFSGYIHYIHMKYDHI----------PGPPRDSF---------------FLGH 51

  Fly    67 DTDQVFTHLRQLAKNS---GDSYLQYSMGFSNFNVIDA-HNAANILNHPNLITK----------- 116
            ..    |.|| |.||:   .|.:|.:...:.....|:. |....::..|..:.:
 Frog    52 SP----TMLR-LMKNNLLMYDHFLGWVQKYGPVVRINGLHRVIILVVSPEAVKELLMSPKYSKDK 111

  Fly   117 --GVIYN-FLHPFLRTGVLTATE-KKWHTRRSML----TRTFHLDILNQFQEIFIAESL--KFVS 171
              .||.| |...|:..|::|..: ..||.:|.::    :||:.:.::..|.|  .||.|  |.:.
 Frog   112 FYDVIANMFGVRFMGKGLVTDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNE--KAEELMEKLME 174

  Fly   172 QFQGQNEVVVSLKDRISRFTLNSICETAMGIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWD 236
            :..|:.|  :.:.|.:||.||:.|.:.|.|::|:.:.:....:.....::.:|:. .:.||:...
 Frog   175 KADGKCE--IKMHDMLSRLTLDVIGKVAFGMELNSLNDDLTPFPKAISLVMKGIV-EMRNPMVRY 236

  Fly   237 DCVYNMFTGHKYNAALKVVHEFSREIIAKRRV-----------LLEEELENRRATQTADDDICVI 290
            ......|. .|...:::::.:..:|.|.:|:.           :|.:.|:.....:..|.:|
 Frog   237 SLAKRGFI-RKVQESIRLLRQTGKECIERRQKQIQDGEEIPVDILTQILKGAAMEEECDPEI--- 297

  Fly   291 RKKRFAMLDTLICAEKDGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEI 355
                  :||..:                  |....|.:||:..|.|.:|.:.......|....||
 Frog   298 ------LLDNFV------------------TFFIAGQETTANQLSFVVMELGRNPEILEKAQAEI 338

  Fly   356 QEHILDDLSNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHV 420
            .| ::....::....|.||.||...:|||:||||:.|...| .|.|..:.:|:.:|:...|.::.
 Frog   339 DE-VIGSKRDIEYEDLGKLQYLSQVLKETLRLYPTAPGTSR-GLTEDMVIDGVKVPENVTIMLNS 401

  Fly   421 FDIHRNPKYWESPEEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHF 485
            :.:.|..:|:..|..|.|:||.|.  ..:..|:|.|||.|.|:||||.::..|.|.:|..:|:.:
 Frog   402 YIMGRMEQYYSDPLTFNPDRFSPD--APKPYYSYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRY 464

  Fly   486 KI-------LPVIDPKSIVFQVGITLRFKNKIKVK 513
            :.       ..::|..::....|:..|.:.:...|
 Frog   465 EFELAEGQSFKILDTGTLRPLDGVICRLRPRTSKK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	113/494 (23%)
cyp46a1.3	NP_001027517.1	p450	40..491	CDD:306555	115/507 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910