Protein Alignment Cyp4p2 and Cyp6a8

DIOPT Version :10

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 554
• Identity: 124/554 - (22%)
• Similarity: 222/554 - (40%)
• Gaps: 111/554 - (20%)

  Fly     5 LLWISVAILVVIHWIYKVNKDYNILAFFARRVQTKDGKPLDSLVPMIKGRTVFANCFDL-LGKDT 68
            |..::||:|.::  .|.:::.   |.:|.||.           :|.:....:..|..:| ..|:.
  Fly     7 LFQVAVALLAIL--TYYIHRK---LTYFKRRG-----------IPFVAPHLIRGNMEELQKTKNI 55

  Fly    69 DQVF-THLRQLAKNS----GDSYLQYSMGFSNFNVIDAHNAANIL--NHPNLITKGVIYNFLHPF 126
            .::| .|..:..::.    |..:.|....|    |||...|..||  :..|...||:.||.....
  Fly    56 HEIFQDHYNKFRESKAPFVGFFFFQSPAAF----VIDLELAKQILIKDFSNFSNKGIFYNEKDDP 116

  Fly   127 LRTGVLTATEKKWHTRRSMLTRTFH-----------LDILNQFQEIFIAESLKFVSQFQGQNEVV 180
            :...:......:|...|:.|:.||.           :.:.|:|..:...:..|         ..|
  Fly   117 ISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK---------NSV 172

  Fly   181 VSLKDRISRFTLNSICETAMGIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDCVYNMFTG 245
            :.::|.::|||::.|...|.||:.:.:.::    :|.|....:   |.:|:..:          |
  Fly   173 LEIRDLVARFTVDVIGTCAFGIQCNSLRDE----KAEFLYFGK---RSLVDKRH----------G 220

  Fly   246 HKYNAALKVVHEFSREIIAKRRVLLEEELENRRATQTADDDICVIRK---KRFAMLDTLI----- 302
            ...|..::...:.:|::...|.....:|..:|..|:|    :.|..|   ||...:|.||
  Fly   221 TLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTET----VAVREKEHIKRNDFMDMLIELKNQ 281

  Fly   303 ---CAEKDGLIDDIGISE---EVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILD 361
               ..|...::..:.:.|   :.......|::|:|..:.|.|..::.....|:....|::|.|..
  Fly   282 KEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQ 346

  Fly   362 DLSNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQE----------TELENGLILPKRSQI 416
            ...|........|.||...:.||:|||..:|.:.|...:.          .|....:|:|..:
  Fly   347 HDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSA-- 409

  Fly   417 NIHVFDIHRNPKYWESPEEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVI 481
                  ||.:|..:..|.|||||||.|:....|...|::||..|.|||||.::...:.:..:.::
  Fly   410 ------IHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALL 468

  Fly   482 LKHFKILP--------VIDPKSIVFQV--GITLR 505
            :::||...        |.||||.|..|  ||.|:
  Fly   469 IRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	CYP4	83..512	CDD:410721	109/470 (23%)
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	107/471 (23%)