Protein Alignment Cyp4p2 and Cyp4a12a

DIOPT Version :9

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_803125.2
• Gene: Cyp4a12a / 277753
• MGIID: 88612
• Length: 508
• Species: Mus musculus
• Alignment Length: 470
• Identity: 141/470 - (30%)
• Similarity: 234/470 - (49%)
• Gaps: 48/470 - (10%)

  Fly    63 LLGKDTDQVFTHLRQLAKNSGDSYLQYSMGFS-NFNVIDAHNAANILNHPNLITKGVIYNFLHPF 126
            |..:|...:.|.:    ||...:..|:..|.. ...|.|......||...:....| .|.||.|:
Mouse    65 LKDQDLQDILTRI----KNFPSACPQWLWGSKVRIQVYDPDYMKLILGRSDPKANG-SYRFLAPW 124

  Fly   127 LRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLKFV----SQFQGQNEVVVSLKDRI 187
            :..|:|....:.|...|.|||..||.|||..:.|| :|:|::.:    .|..||:..:...: .|
Mouse   125 IGRGLLMLDGQTWFQHRRMLTPAFHYDILKPYTEI-MADSVRVMLDKWEQIVGQDSTLEIFR-HI 187

  Fly   188 SRFTLNSICETAM----GIKLDEMAEKGDRYRANFHIID---EGLTRRIVNPLYWDDCVYNMFT- 244
            :..||::|.:.|.    .::||.      :|::....::   :.:..|:.|..:.:|.:|.:.:
Mouse   188 TLMTLDTIMKCAFSHEGSVQLDR------KYKSYIQAVEDLNDLVFSRVRNIFHQNDIIYRVSSN 246

  Fly   245 GHKYNAALKVVHEFSREIIAKRRVLL--EEELENRRATQTADDDICVIRKKRFAMLDTLICA--E 305
            |.|.|:|.|:.|:.:.::|..||:.|  |||||..:            :|:|...||.|:.|  |
Mouse   247 GCKANSACKLAHDHTDQVIKSRRIQLQDEEELEKLK------------KKRRLDFLDILLFARME 299

  Fly   306 KDGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSNLNLSQ 370
            ....:.|..:..||||.|.||:|||:.|:.:....::.....|:.|.:|||. :|.|.:::..:.
Mouse   300 NGKSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQS-LLGDGTSITWND 363

  Fly   371 LSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYWESPEE 435
            |.|:.|....|||.:|:||.:|.:.|:........:|..|||...:.:..:.:|.||..|.:||.
Mouse   364 LDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVWPNPEV 428

  Fly   436 FRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQV 500
            |.|.||.|.:  .||.::::|||.|.|||||:::||.|:|..:.:.|..|::||  ||..:...:
Mouse   429 FDPSRFAPGS--SRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP--DPTRVPIPI 489

  Fly   501 -GITLRFKNKIKVKL 514
             .|.|:.||.|.:.|
Mouse   490 PRIVLKSKNGIHLHL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	140/468 (30%)
Cyp4a12a	NP_803125.2	p450	52..502	CDD:278495	140/466 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845077
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850