Protein Alignment Cyp4p2 and CYP4X1

DIOPT Version :9

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_828847.1
• Gene: CYP4X1 / 260293
• HGNCID: 20244
• Length: 509
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 119/428 - (27%)
• Similarity: 215/428 - (50%)
• Gaps: 24/428 - (5%)

  Fly    96 FNVIDAHNAANILNHPNLITKGVIYNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQE 160
            |.:.|...|..:|:..:..:: .:..|..|.|..|:......||...|.:||..||.:||..:.|
Human    91 FCIYDPDYAKTLLSRTDPKSQ-YLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIE 154

  Fly   161 IFIAESLKFV----SQFQGQNEVVVSLKDRISRFTLNSICETAMGIKLD-EMAEKGDRYRANFHI 220
            : :|.|:|.:    .:.....:..|.:.:.|:..:|:.|.:.|...:.: :.....|.|......
Human   155 V-MAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPYAKAIFE 218

  Fly   221 IDEGLTRRIVNPLYWDDCVYNMF-TGHKYNAALKVVHEFSREIIAKRRVLLEEELENRRATQTAD 284
            :.:.:..|:.:.||..|.::.:. .|:::....:|:::::..||.:|:..|:..::.....
Human   219 LSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQAGVKQDNTP---- 279

  Fly   285 DDICVIRKKRFAMLDTLICA--EKDGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAE 347
                  ::|....||.::.|  |......||.:..||.|.:..|:||.:..:.:.|..::|....
Human   280 ------KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEH 338

  Fly   348 QELCYQEIQEHILDDLSNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPK 412
            ||.|.:|:: .||.|.|::...||.:::|....||||.||.|::|.:.|...:.....:|..||.
Human   339 QERCREEVR-GILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPA 402

  Fly   413 RSQINIHVFDIHRNPKYWESPEEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTL 477
            ...:.:.::.:|.||..|::|:.|.|.||..:|..:||||||:|||||.||||||::||.|:|..
Human   403 GITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVT 467

  Fly   478 MVVILKHFKILPVIDP-KSIVFQVGITLRFKNKIKVKL 514
            :.:||.||::.|  || :.:.|.....|:.||.:.:.|
Human   468 IALILLHFRVTP--DPTRPLTFPNHFILKPKNGMYLHL 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	118/426 (28%)
CYP4X1	NP_828847.1	p450	47..501	CDD:306555	118/424 (28%)
		heme binding region	447..460		10/12 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154834
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850