Protein Alignment Cyp4p2 and Cyp19a1

DIOPT Version :9

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_058781.2
• Gene: Cyp19a1 / 25147
• RGDID: 2457
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 466
• Identity: 107/466 - (22%)
• Similarity: 193/466 - (41%)
• Gaps: 113/466 - (24%)

  Fly    71 VFTHLRQLAKNSGDSYLQYSMGFSNFN-----------VIDAHNAANILNHPNLITK-------- 116
            :.:|.|.|....|.:...|:..:..|.           :..:.:..:::.|.|.|::
  Rat    59 LISHGRFLWMGIGSACNYYNKMYGEFMRVWISGEETLIISKSSSMVHVMKHSNYISRFGSKRGLQ 123

  Fly   117 -------GVIYNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLK------ 168
                   |:|:| .:|.|           |.|.|....:......|.:..|:.: ||:|
  Rat   124 CIGMHENGIIFN-NNPSL-----------WRTVRPFFMKALTGPGLIRMVEVCV-ESIKQHLDRL 175

  Fly   169 -FVSQFQGQNEVVVSLKDRISRFTLNSICETAMGIKLDE--MAEKGDRYRANFHIIDEGLTRRIV 230
             .|:...|..: ||:|...|...|.|::   .:||.|||  :.:|...|...:..:       ::
  Rat   176 GDVTDNSGYVD-VVTLMRHIMLDTSNTL---FLGIPLDESSIVKKIQGYFNAWQAL-------LI 229

  Fly   231 NP-----LYWDDCVYNMFTGHKYNAALKVVHEFSREIIAKRR--VLLEEELENRRATQTADDDIC 288
            .|     :.|   :|     .||..::|.:.:....::.|:|  |...|:||:           |
  Rat   230 KPNIFFKISW---LY-----RKYERSVKDLKDEIEILVEKKRQKVSSAEKLED-----------C 275

  Fly   289 VIRKKRFAMLDTLICAEKDGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQ 353
            :    .||  ..||.||:.|.:....:::.:..::....||.|:.|..    |.|..||    |.
  Rat   276 M----DFA--TDLIFAERRGDLTKENVNQCILEMLIAAPDTMSVTLYV----MLLLIAE----YP 326

  Fly   354 EIQEHILDDL------SNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPK 412
            |::..||.::      .::.:..:..|..:..||.|::|..|.:.::.|:.| |.::.:|..:.|
  Rat   327 EVETAILKEIHTVVGDRDIRIGDVQNLKVVENFINESLRYQPVVDLVMRRAL-EDDVIDGYPVKK 390

  Fly   413 RSQINIHVFDIHRNPKYWESPEEFRPERFLPQNCLKRHPYAYI-PFSAGQRNCIGQKYAMQEMKT 476
            .:.|.:::..:|| .:|:..|.||..|.|     .|..||.|. ||..|.|:|.|:..||..||.
  Rat   391 GTNIILNIGRMHR-LEYFPKPNEFTLENF-----EKNVPYRYFQPFGFGPRSCAGKYIAMVMMKV 449

  Fly   477 LMVVILKHFKI 487
            ::|.:||.|.:
  Rat   450 VLVTLLKRFHV 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	107/466 (23%)
Cyp19a1	NP_058781.2	CYP19A1	72..485	CDD:410709	103/453 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348764
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040