Protein Alignment Cyp4p2 and Cyp4a2

DIOPT Version :10

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001038235.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 474
• Identity: 138/474 - (29%)
• Similarity: 233/474 - (49%)
• Gaps: 57/474 - (12%)

  Fly    62 DLLGKDTDQVFTHLRQLAKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITKGVI------- 119
            :|..::..||.|.:.:..    .:.||:..|          :.|.:|.:.....|.|:
  Rat    63 NLKDREFQQVLTWVEKFP----GACLQWLSG----------STARVLLYDPDYVKVVLGRSDPKP 113

  Fly   120 YNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLKFV----SQFQGQNEVV 180
            |..|.|::..|:|....|||...|.|||..||.|||..:.:| :|:|:..:    .:...|:. .
  Rat   114 YQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKI-MADSVSIMLDKWEKLDDQDH-P 176

  Fly   181 VSLKDRISRFTLNSICETAM----GIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDCVYN 241
            :.:...:|..||:::.:.|.    .::||..:..   |......::..:..|:.:..|.:..:||
  Rat   177 LEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRS---YTKAVEDLNNLIFFRVRSAFYGNSIIYN 238

  Fly   242 MFT-GHKYNAALKVVHEFSREIIAKRRVLL--EEELENRRATQTADDDICVIRKKRFAMLDTLIC 303
            |.: |.....|.::.||.:..:|..|:..|  ||||:..|            :|:....||.|:.
  Rat   239 MSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKAR------------KKRHLDFLDILLF 291

  Fly   304 AE-KDG-LIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSNL 366
            |: :|| .:.|..:..||||.|.||:|||:.|:.:....::.:...||.|.:|:|. ||.|.:::
  Rat   292 AKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQS-ILGDGTSV 355

  Fly   367 NLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYWE 431
            ....|.::.|....|||.:|||..:|.:.|:........:|..:||..::.|.::.:|.||.||.
  Rat   356 TWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWP 420

  Fly   432 SPEEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSI 496
            :|:.|.|.||.|.:  .||.:||:|||.|.|||||:::||.|:|..:.:.|..|::||  ||..|
  Rat   421 NPKVFDPSRFSPDS--PRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP--DPTRI 481

  Fly   497 -VFQVGITLRFKNKIKVKL 514
             |....:.|:.||.|.::|
  Rat   482 PVPMPRLVLKSKNGIHLRL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	CYP4	83..512	CDD:410721	133/449 (30%)
Cyp4a2	NP_001038235.1	CYP4B-like	69..499	CDD:410771	136/465 (29%)