DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p2 and Cyp4f17

DIOPT Version :9

Sequence 1:	NP_610472.1	Gene:	Cyp4p2 / 35946	FlyBaseID:	FBgn0033395	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001094915.1	Gene:	Cyp4f17 / 208285	MGIID:	3646233	Length:	524	Species:	Mus musculus

Alignment Length:	407	Identity:	127/407 - (31%)
Similarity:	200/407 - (49%)	Gaps:	39/407 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 LNHPNLI------------TKGVIYNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQE 160
            |.||..|            .:.:.|.||.|:|..|:|.:..:||...|.:||..||.|||..:.:
Mouse   101 LIHPKFIGPILQASAAVAPKEMIFYGFLKPWLGDGLLVSAGEKWSRHRHLLTPAFHFDILKPYMK 165

  Fly   161 IFIAESLKFV----SQFQGQNEVVVSLKDRISRFTLNSICETAMGIKLDEMAEKGDRYRANFHII 221
            .| .:|:..:    .:...:....:.:.:.||..||:|:........ ....|....|.|....:
Mouse   166 NF-NKSVNIMHAKWQRLTTKGTACLDMLEHISLMTLDSLQNCVFSFD-SNCQESPSEYIAAIQEL 228

  Fly   222 DEGLTRRIVNP-LYWDDCVYNMFTGHKYNAALKVVHEFSREIIAKRRVL-----LEEELENRRAT 280
            ...:.:|...| ||.|...|....|.::..|..:||.|:..:|.:||..     |:|.|:::..:
Mouse   229 SSLIVKRHHQPFLYLDFLYYCTADGRRFRKACDLVHNFTDAVIRERRRTLSSQNLDEFLKSKTKS 293

  Fly   281 QTADDDICVIRKKRFAMLDTLICA--EKDGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSL 343
            :|.|            .:|.|:.|  |....:.|..|..|.||.|..|:|||:..|.:.|.|::.
Mouse   294 KTLD------------FIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLAR 346

  Fly   344 YAAEQELCYQEIQEHILD-DLSNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENG 407
            :...||.|.||:||.:.. :...:....|::|.:|...|||::||:|.:.::.|...|:..|.:|
Mouse   347 HPEYQERCRQEVQELLRGREPQEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDVVLPDG 411

  Fly   408 LILPKRSQINIHVFDIHRNPKYWESPEEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQ 472
            .::||.:...|.:|.:|.||:.|..||.:.|.||.|:|..||.|.|:||||||.||||||.:||:
Mouse   412 RVIPKGTDCVISIFGVHHNPEVWPDPEVYDPFRFDPENPQKRSPLAFIPFSAGPRNCIGQTFAMR 476

  Fly   473 EMKTLMVVILKHFKILP 489
            |||..:.:.|..|::||
Mouse   477 EMKVALALTLLRFRVLP 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	127/407 (31%)
Cyp4f17	NP_001094915.1	p450	52..515	CDD:365848	127/407 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845320
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2076
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.880