Protein Alignment Cyp4p2 and cyp-13B2

DIOPT Version :10

• Sequence 1: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_510369.2
• Gene: cyp-13B2 / 187068
• WormBaseID: WBGene00010606
• Length: 511
• Species: Caenorhabditis elegans
• Alignment Length: 577
• Identity: 126/577 - (21%)
• Similarity: 214/577 - (37%)
• Gaps: 127/577 - (22%)

  Fly     1 MMICLLWISVAILVVIHWIYKVNKDYNILAFFARR-VQTKDGKPLDSLVPMIKGRTVFANCFDLL 64
            :::||:.|...:.....||:         :::.|| ::...|.|.            ..:.:||.
 Worm     3 VIVCLVAIIGVVAGYFKWIH---------SYWKRRGIEGPVGLPF------------IGSFYDLA 46

  Fly    65 GKDTDQVFTHLRQLAKNSGDSYLQY----------------SMGFSNFNVIDAHNAANILNHPNL 113
            .::..:.|. :.:..|..|..:..|                .|....|:...|....|:: |.||
 Worm    47 DREKPRGFI-INKWTKMFGKVFGYYEGVIPVLVVSDLDMLQEMFIKKFDCFYARKTTNLI-HGNL 109

  Fly   114 ITKGVIYNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLKFVSQFQGQ-N 177
            .....     .|  |..:..|...:|...|::.:..|.:..|.|..|.........|.....| |
 Worm   110 ECSQE-----EP--RVNLFAARGARWKRLRALASPAFSVKALKQIHETMEDSVFSMVDHMSKQVN 167

  Fly   178 EVVVSLKDRISRFTLNSICETAMGIKLDEMAEKGDRYRANFHIIDEG--------LTRRIVNPLY 234
            ....::.:....||.:.|...||          |..|...|:  :||        |.:..|.|.|
 Worm   168 GEAFNIHEYYQEFTYDVISRLAM----------GQTYSEQFN--NEGVDIVKKIFLRKNRVYPWY 220

  Fly   235 -------WDDCVYNMFTGHK------YNAALKVVHEFSREIIAKRRVLLEEELENRRATQTADDD 286
                   :::.:.|.|..|:      ....||.......:.:.:|...:|:.:||      ..:|
 Worm   221 LAVMFPGFENTIKNTFFNHEAVRGGDVGKLLKFCETAVHDRLKERADNVEQGIEN------PHND 279

  Fly   287 ICVIRKKRFAMLDTLICAEKDGLIDD--IGI-------SEEV----DTLMAEGYDTTSIGLVFGL 338
                      .:|..:....|..|:|  .||       ||:|    ...:..|:|||:..|.:..
 Worm   280 ----------FIDMFLDYYTDTNIEDNAFGIKVEKKVTSEDVIGACFVFLLAGFDTTANTLAYAS 334

  Fly   339 MNMSLYAAEQELCYQEI-----QEHILDDLSNLNLSQLSKLNYLGYFIKETMRLYP-SIPIMGRQ 397
            ..::.:..|......||     .|||..|       .:.||.|:...|:|.:|:|| :.....|:
 Worm   335 YLLAKHPQEMRKVQDEIDRICTSEHISYD-------DIGKLRYMDAVIREALRMYPVAWFACSRE 392

  Fly   398 TLQETELENGLILPKRSQINIHVFDIHRNPKYW-ESPEEFRPERFLPQNCLKRHPYAYIPFSAGQ 461
            .:|.|.|.| ..:.|..:|...|..:|.:.:.| ::..||.|||:|..:  .||..::|||.||.
 Worm   393 CVQATTLGN-YYIEKGVRIEADVRALHYSEEIWGKNANEFVPERWLESS--PRHNMSWIPFGAGP 454

  Fly   462 RNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQVGITLRFKNKIKVKLVRRN 518
            |.|:|.:..:.|.||.:..:|:.|.||.....:..:...|.|.....|:.|.|:.|:
 Worm   455 RQCVGMRLGLSEAKTALAHLLRRFSILAGPKTEKELHLQGCTTTSPEKVTVHLMTRD 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p2	NP_610472.1	CYP4	83..512	CDD:410721	110/486 (23%)
cyp-13B2	NP_510369.2	CYP3A-like	62..505	CDD:410678	110/488 (23%)